Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-626-1 | CAS number: 98-00-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- no data
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Information from publshed review; adequate for consideration as part of a weight of evidence assessment.
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Criteria for a recommended standard – occupational exposure to furfuryl alcohol.
- Author:
- US National Institute for Occupational Safety & Health
- Year:
- 1 979
- Bibliographic source:
- DHEW (NIOSH) Publication 79-133
- Reference Type:
- other: primary citation; company data
- Title:
- Physiological data on furfuryl alcohol Project 1011-B, Report No 2,Chicago
- Author:
- Woods LA & Seevers MH
- Year:
- 1 954
- Bibliographic source:
- The Quaker Oats Co, Chemicals Division, 15 pp (cited in NIOSH, 1979)
Materials and methods
- Principles of method if other than guideline:
- Undiluted furfuryl alcohol was instilled, slowly into one eye of each of 4 rabbits.
- GLP compliance:
- no
Test material
- Reference substance name:
- Furfuryl alcohol
- EC Number:
- 202-626-1
- EC Name:
- Furfuryl alcohol
- Cas Number:
- 98-00-0
- Molecular formula:
- C5H6O2
- IUPAC Name:
- (furan-2-yl)methanol
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- unchanged (no vehicle)
- Controls:
- no
- Amount / concentration applied:
- 0.05 mL or 56 mg
- Duration of treatment / exposure:
- single instillation
- Observation period (in vivo):
- 64 days
- Number of animals or in vitro replicates:
- 4
Results and discussion
In vivo
Results
- Irritation parameter:
- other: eye irritation observations
- Basis:
- other: all 4 rabbits
- Time point:
- other: up to 64 days
- Reversibility:
- fully reversible within: 40-64 days
- Remarks on result:
- other: instillation resulted in eye inflammation, viscid mucoid secretion, corneal opacity and eyelid swelling
Any other information on results incl. tables
Instillation with 0.02 mL (23 mg) produced the same but less severe effects, with recovery after 2-8 days.
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information
- Conclusions:
- Furfuryl alcohol was irritating to rabbit eyes after instillation of 0.05 mL (56mg) and 0.02 mL (23 mg) with recovery after 40-64 days and 2-8 days respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.