Registration Dossier
Registration Dossier
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EC number: 700-455-1 | CAS number: 380843-75-4
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 July 2009 - 4 August 2009
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
- Principles of method if other than guideline:
- Crystales of 3509 were imaged using polarized light on the Zeiss Axio Optical Microscope at 50x magnification.
Four crystals were chosen and measurements were taken using Image-Pro Plus 6.0. - GLP compliance:
- not specified
- Type of distribution:
- other: Photomicroscopy
Test material
- Reference substance name:
- 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
- EC Number:
- 700-455-1
- Cas Number:
- 380843-75-4
- Molecular formula:
- C26H29Cl2N5O3
- IUPAC Name:
- 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
Constituent 1
Results and discussion
Particle size
- Percentile:
- D50
- Remarks on result:
- other: Aspect Ratio: 1.5(migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)
Any other information on results incl. tables
Lenght (um) Width (um) Aspect Ratio
Crystal 1 316 213 1.48
Crystal 2 291 205 1.42
Crystal 3 484 328 1.48
Crystal 4 278 193 1.44
Average: 1.46
Applicant's summary and conclusion
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