Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
2.82 mg/m³
DNEL related information
Dose descriptor starting point:
other: Derivation of the inhalation DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
2.82 mg/m³
DNEL related information
Dose descriptor:
other: Derivation of the inhalation DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Workers - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.43 mg/kg bw/day
DNEL related information
Dose descriptor starting point:
other: Derivation of the dermal DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified

Workers - Hazard for the eyes

Local effects

Hazard assessment conclusion:
no hazard identified

Additional information - workers

In order to evaluate toxicological properties of the substance 2 -ethylhexanoic acid, zirconium salt, information on the assessment entities zirconium cation and 2 -ethylhexanoate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for 2-ethylhexanoic acid, zirconium salt.

General Population - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.7 mg/m³
DNEL related information
Dose descriptor starting point:
other: Derivation of the inhalation DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.7 mg/m³
DNEL related information
Dose descriptor:
other: Derivation of the inhalation DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.21 mg/kg bw/day
DNEL related information
Dose descriptor starting point:
other: Derivation of the dermal DNELs for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
no hazard identified
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified

General Population - Hazard via oral route

Systemic effects

Long term exposure
Hazard assessment conclusion:
DNEL (Derived No Effect Level)
Value:
0.2 mg/kg bw/day
DNEL related information
Dose descriptor starting point:
other: Derivation of the oral DNEL for 2-ethylhexanoic acid, zirconium salt is based on the point of departure for the most sensitive endpoint for each individual constituent (zirconium and 2-ethylhexanoic acid).
Acute/short term exposure
Hazard assessment conclusion:
no hazard identified
DNEL related information

General Population - Hazard for the eyes

Local effects

Hazard assessment conclusion:
no hazard identified

Additional information - General Population

In order to evaluate toxicological properties of the substance 2 -ethylhexanoic acid, zirconium salt, information on the assessment entities zirconium cation and 2 -ethylhexanoate anion were considered. For a documentation and justification of that approach, please refer to the separate document attached to section 13, namely Read Across Assessment Report for 2-ethylhexanoic acid, zirconium salt.