Registration Dossier
Registration Dossier
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EC number: 700-991-6 | CAS number: 8007-24-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Endpoint to be waived because from the compositional description and the exceedingly low water solubility demonstrated (0.3 mg /l) it can be concluded that Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled (Distilled grade) is not expected to demonstrate adverse effects in an acute test. Therefore, Distilled grade should not require testing to determine its acute toxicity to invertebrates based on the reason for waiving as defined in Column 2 - Specific Rules for Adaptation from Colum 1 of the REACH Regulation (i.e. the study does not need to be conducted if: there are mitigating factors indicating that aquatic toxicity is unlikely to occur, for instance if the substance is highly insoluble in water or the substance is unlikely to cross biological membranes). This approach is consistent with the absence of short-term effects at the water solubility limit in a study in which the marine invertebrate Acartia tonsa was exposed to Technical grade. A long-term sub-lethal test using the invertebrate Daphnia magna has been conducted which is consistent with Column 2 - Specific Rules for Adaptation from Column 1 of the REACH Regulation for substances that are poorly water soluble (i.e. water solubility <1mg/l).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.3 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 0.3 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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