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EC number: 289-450-9 | CAS number: 88895-93-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
No study on ready biodegradability is available for fatty acids, C18-unsatd. Therefore, read across from the key studies of oleic acid (C18, 1 double bond, 9-Octadecenoic acid, (Z)-) and stearic acid, (C18, saturated) was done as well as QSAR predictions on ready biodegradability.
Coenen (1991) conducted a GLP study according to OECD 301B. After 28 days 93% and 75% of oleic acid were biodegraded at concentrations of 10 mg/L and 20 mg/L, respectively und thus passed the 60% degradation level. Furthermore, at the lower test concentration of 10 mg/L the 10-day window was met. According to the criteria for ready biodegradation oleic acid (9-Octadecenoic acid, (Z)-) is readily biodegradable. Since the reference substance itself failed the pass criterion for validity (60% degradation was not reached within 14 d), the study should had been repeated.
The
stearic acid, saturated was tested by Bogers (1989) for ready
biodegradability according to OECD 301B and GLP. At concentrations of 10
and 20 mg/L the degradation values were 72% and 71%, respectively at
test termination (28 d). The pass criterion for ready biodegradability
(60% degradation reached within 10 days once exceeded 10% degradation)
was barely missed. However, the sampling interval was not as narrow as
recommended by the OECD guideline (sampling every second day, followed
by sampling every fifth day) which might have led to the barely missing
of the 10-day window.
The failure of the 10-day window in biodegradation tests due to the low
water solubility/bioavailability as well as to the inappropriate
sampling intervals were already recognized and discussed within the
framework of the SIDS Initial Assessment Report for the Category
“Aliphatic Acids” (OECD, 2009) and judged not to preclude the ready
biodegradability of the fatty acids.
Results of the QSAR model BIOWIN v.4.10 (EPI Suite, 2010) predicts ready biodegradability for fatty acids, C18-unsatd. This method is based on the application of Bayesian analysis to ready biodegradation data for chemicals, derived collectively from all six OECD301 test methods plus OECD310.
Overall, the fatty acids, C18-unsatd. is regarded as readily biodegradable. This judgment is consistent with the hazard assessment presented in the OECD SIDS (2009) for the category “Aliphatic Acids Category” where aliphatic fatty acids with a carbon chain length in the range of C8 – C22 were judged to be readily biodegradable.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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