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Diss Factsheets
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EC number: 204-111-7 | CAS number: 115-84-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Endpoint summary
Administrative data
Description of key information
Additional information
Juvenile O. mykiss were exposed to 2 -butyl-2 -ethylpropanediol (BEPD) at nominal concentrations of 4.6, 10, 22, 46 and 100 mg/L in a semi-static 96 -hour acute toxicity test according to OECD 203 guidelines. The test design included an untreated control comprising of dilution water only. Concentrations of BEPD were verified analytically at test initiation and termination and mean measured concentrations were 92 to 119% of nominal. The 96 -hour LC50 determined was >100 mg BEPD/L (mean measured). The NOEC (no-observed effect concentration) was 23 mg BEPD/L (Bell, 1995).
The 48 hour acute toxicity of BEPD to Daphnia magna was carried out in a static system according to OECD 202 and EU guidelines. First instar daphnids were exposed over a 48 hour period to BEPD at nominal concentrations of 0 (control) and 100 mg/L. Duplicate, loosely covered vessels, each containing 10 daphnids in 200 ml medium were allocated to each treatment. Concentration of BEPD was verified analytically at test initiation and termination and mean measured concentration was 95 mg/L. Individual pH, temperature and dissolved oxygen values remained within acceptable limits throughout the duration of the study. The 48-hour EC50 was determined to be >100 mg BEPD/L (nominal) (Bell, 1995).
S. capricornutum was exposed to BEPD at nominal concentrations of 2.2, 4.6, 10, 22, 46 and 100 mg/L in a static 72 -hour toxicity test carried out according to OECD 201 guidelines. The test design included an untreated control comprising untreated algal growth medium only. Concentrations of BEPD were verified analytically at test initiation and termination and measured concentrations were 91 - 98% of nominal. The 72 -hour ErC50 and EbC50 endpoints determined were >100 and 94 mg BEPD/L, respectively. The corresponding 72 -hour NOEC based on inhibition of specific growth rate, determined using Williams' test analysis, was 45 mg BEPD/L (Bell, 1995).
Activated sludge obtained from a sewage treatment plant was exposed in a 3 -hour respiration inhibition test to concentrations of 0, 51.1, 103, 258, 515 and 2575 mg BEPD/L. The test design included duplicate samples and followed OECD 209 guidelines. The 3 -hour EC50 based on respiration inhibition was 650 mg BEPD/L (Solyom, 1998).
In the chemical safety assessment performed according to Article 14(3) in connection with Annex I section 3 (Environmental Hazard Assessment) no hazard was identified. Therefore according to REACH Annex I (5.0) exposure estimation is not necessary for long-term toxicity to fish and aquatic invertebrates. Consequently, in accordance with Column 2 of REACH Annex IX, the studies do not need to be conducted as all identified uses of the substance are assessed as safe for the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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