Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-745-7 | CAS number: 149-73-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_guidance-on-safe-use.png)
Guidance on Safe Use
Administrative data
First-aid measures
EYE CONTACT
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
SKIN CONTACT
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid.
INGESTION
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
INHALATION
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Fire-fighting measures
EXTINGUISHING MEDIA
This substance is a highly flammable liquid category 2 (CLP). Use water spray to cool fire-exposed containers. This material is lighter than water and not very soluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. Do NOT use straight streams of water. For small fires, use dry chemical, carbon dioxide, water spray or regular foam. Cool containers with flooding quantities of water until well after fire is out. For large fires, use water spray, fog or regular foam.
Flashpoint: 13 degrees C (closed cup).
Explosion limits LEL 1.4%, UEL 44.6%
SPECIAL FIRE FIGHTING PROCEDURES
None.
UNUSUAL FIRE & EXPLOSION HAZARDS
Highly flammable liquid and vapour. Containers may explode when heated.
SPECIFIC HAZARDS
Vapours may be heavier than air. They can spread along the ground and collect in low or confined areas.
PROTECTIVE MEASURES IN FIRE
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH -approved or equivalent, and full protective gear. Vapours may form an explosive mixture with air. Vapours can travel to a source of ignition and flash back. Use water spray to keep fire-exposed containers cool.
Accidental release measures
PERSONAL PRECAUTIONS
See below
EXPOSURE LIMITS:None listed.
USE LIMITS: Only to be handled in an industrial environment as industrial feedstock for further chemical synthesis.
.
ENVIRONMENTAL PRECAUTIONS
Take precautionary measures against discharges into the environment.
SPILL CLEAN UP METHODS
Remove all sources of ignition and absorb spilled material with inert material, then place into a suitable closed container for disposal as chemical waste. A vapour suppressing foam may be used to reduce vapours.
Water spray may reduce vapour but may not prevent ignition in closed spaces.
Handling and storage
USAGE PRECAUTIONS
Use with adequate ventilation and avoid inhalation. Avoid contact with eyes, skin or clothing.
Ground and bond containers when transferring material.
Wash thoroughly after handling and before eating, drinking or smoking.
Empty containers retain product residue and can be dangerous (highly flammable liquid and/or vapour)
Keep containers tightly closed and avoid contact with heat, sparks and flames. Do not pressurise, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
STORAGE PRECAUTIONS
To protect product quality, store in sealed container out of direct sunlight.
Keep away from heat, sparks and flames and other sources of ignition.
Store in a tightly closed container in a cool, dry and well ventilated place away from incompatible substances such as acids or strong oxidising agents
Transport information
Shippingopen allclose all
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
Shippingopen allclose all
Remarksopen allclose all
Shippingopen allclose all
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
EXPOSURE LIMITS
None listed.
USE LIMITS
Only to be handled in an industrial environment as industrial feedstock for further chemical synthesis
PNECs:
aqua-freshwater: 1.572 mg/L
aqua-marine water: 0.1572 mg/L
aqua-intermittent: 15.72 mg/L
sewage treatment plant: 0.672 mg/L
sediment-freshwater: 1.37 mg/kg dw
sediment-marine water: 0.137 mg/kg dw
soil: 2.99 mg/kg dw
DNELs:
The main derived long-term DNELs for systemic effects are:
Workers General population
Oral not relevant 1.73 mg/kg bw/day
Dermal 3.46 mg/kg bw/day 1.73 mg/kg bw/day
Inhalation 3.05 mg/m3 0.753 mg/m3
The Chesar version 2.3.0 exposure model shows for this substance for indoor industrial activities taking more than 4 hours/day, with local exhaust ventilation (LEV) present (and running), provided workers wear masks with at least 90% respiratory protection and gloves with at least 90% dermal protection, the following exposures:
Inhalation (mg/m3) dermal (mg/kg/day) RCR (inh) RCR (dermal) RCR (total)
PROC1 0.003 0.003 < 0.01 < 0.01 < 0.01
Use in closed process, no likelihood of exposure
PROC2 0.155 0.014 0.051 < 0.01 0.055
Use in closed, continuous process with occasional controlled exposure
PROC3 0.309 0.007 0.102 < 0.01 0.104
Use in closed batch process (synthesis or formulation)
PROC4 0.619 0.069 0.203 0.02 0.223
Use in batch and other process (synthesis) where opportunity for exposure arises
PROC5 1.548 0.137 0.507 0.04 0.547
Use in closed batch process (synthesis or formulation)
PROC8a 1.548 0.137 0.507 0.04 0.547
Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at non-dedicated facilities
PROC8b 0.387 0.069 0.127 0.02 0.147
Transfer of substance or preparation (charging/discharging) from/to vessels/large containers at dedicated facilities
PROC9 1.548 0.069 0.507 0.02 0.527
Transfer of substance or preparation into small containers (dedicated filling line, including weighing)
PROC15 0.309 0.003 0.102 < 0.01 0.103
Use as laboratory reagent
The applied RMMs/OCs will not control the risks of the highly flammability of liquid and vapour (H225).
Notes:
• Good general ventilation is assumed in all cases (3-5 air exchanges per hour)
• LEV is considered for both inhalation and dermal exposures and its efficiencies are as follows:
o For PROC1 LEV is not an exposure modifier
o For PROC2, PROC3, PROC4, PROC5, PROC8a, PROC9 and PROC15 LEV reduces both inhalation and dermal exposure with 90%
o For PROC8b LEV reduces both inhalation and dermal exposure with 95%
The same CHESAR tool predicts the following for the relevant ERCs (ERC2, ERC6a, ERC6b) at a level of 1000 ton/y (fraction of tonnage to region = 1):
Total daily intake man via the environment regional RCR < 0.01
ERC2 = Formulation
ERC6a = Industrial use resulting in manufacture of another substance (use of intermediates)
ERC6b = Industrial use of reactive processing aids
PROTECTIVE EQUIPMENT
Protective gloves, safety goggles, breathing apparatus and protective clothing. Avoid any source of ignition and/or static charge.
RESPIRATORY EQUIPMENT
Wear positive pressure self-contained breathing apparatus classified under EN 137:2006 and give operators basic training. Cartridges must be
discarded after each working day.
HAND PROTECTION
Wear appropriate protective gloves to prevent skin exposure. Use chemically resistant gloves classified under EN 374, class 6 (breakthrough time >
480 minutes). Give operators basic training. An advanced occupational health and safety management system must be in use. Discard gloves after
one working day or when they have come into direct contact with the substance.
EYE PROTECTION
Wear approved safety goggles classified under EN 166:2001.
HYGIENE MEASURES
Wash at the end of each work shift and before eating, drinking, smoking or using the toilet.
SKIN PROTECTION
Wear protective clothing and boots.
Stability and reactivity
STABILITY
Stable under normal temperature conditions and recommended use.
MATERIALS TO AVOID
Strong oxidising agents, acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Disposal considerations
GENERAL INFORMATION
Place into a suitable closed container for disposal as chemical waste3
DISPOSAL METHODS
Dispose of in accordance with local and national regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
![ECHA](/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/echa_logo.png)