Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
an in vivo study is available and shown in this record
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
ECB
Year:
2000
Bibliographic source:
Iuclid4 data set, 18/02/2000

Materials and methods

Test guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Trimethyl orthoformate
EC Number:
205-745-7
EC Name:
Trimethyl orthoformate
Cas Number:
149-73-5
Molecular formula:
C4H10O3
IUPAC Name:
trimethoxymethane

Test animals

Species:
rabbit

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Time point:
other: according to OECD TG404
Score:
0
Irritation parameter:
edema score
Time point:
other: according to OECD TG404
Score:
0

Any other information on results incl. tables

Not irritating

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU