Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 416-740-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
Sediment toxicity:
Short-term toxicity to sediment invertebrates: 14-day mortality and growth test in Hyalella azteca and Chironomus tentans- key study for read-across DIDP surrogate- did not cause toxicity.
Conclusion: Read-across results from the structurally related isomeric phthalate surrogate, namely, DIDP (CAS No. 68515-49-1) indicate that the submission substance is not expected to cause toxicity to sediment invertebrates at high sediment loading levels of greater than 3000 mg/kg
Key value for chemical safety assessment
Additional information
Data directly evaluating the sediment toxicity of the submission substance are not available. However, there are sufficient read-across short-term sediment toxicity data reported for the isomeric alkyl phthalate analogues such as diisodecyl phthalate (DIDP) (CAS No. 68515-49-1), which can provide some useful read-across assessment for terephthalate congener materials like the submission substance. From a structure activity relationship perspective, the long-chain alkyl phthalates and the corresponding long-chain terephthalates are chemically similar and related in that they are isomeric analogs of each other. From a toxicological perspective, one would expect terephthalates (i.e., 1,4-benzenedicarboxylic acid, diesters) to have similar toxicity to the corresponding phthalate materials (i.e., 1,2-benzenedicarboxylic acid, diesters) owing to their similar physical chemical characteristics (e.g., water insolubililty, log Kow, and bioavailability). Hence, the available read-across sediment toxicity data for alkyl phthalate esters surrogate such as DIDP, can help assess the potential toxicity of the submission terephthalate material (EC No. 416-740-6), especially in sediment invertebrates.
The read-across data for structurally related isomeric phthalate surrogate, namely, DIDP (CAS 68515 -49 -1) indicate that submission substance is not likely to produce toxicity to sediment dwellers at high sediment loadings (e.g., 3000 mg/kg). The sediment invertebrate dataset includes results for Chironomus tentans and Hyalella azteca
Reference: Call D et al. (2001). An assessment of the toxicity of phthalate esters to freshwater benthos. 2. Sediment expousres. Environ. Toxicol. Chem. 20(8): 1805 -1815.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.