Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 416-740-6 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2010 Calculated
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Reliability rating was 2 because the data were calculated
- Qualifier:
- according to guideline
- Guideline:
- other: computer model
- Principles of method if other than guideline:
- Hydrolysis rate calculated by HYDROWIN v2.00 in EPI Suite v 4.0 computer model. Computational method was based on work for EPA by T. Mill et al.
- GLP compliance:
- no
- Radiolabelling:
- no
- Transformation products:
- no
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- 1.569 yr
- pH:
- 8
- Temp.:
- 25 °C
- DT50:
- 57.292 d
- Validity criteria fulfilled:
- yes
- Conclusions:
- Hydrolysis will not significantly contribute to the removal of the test substance from the environment.
The hydrolysis half-life was calculated as follows (at 25 degree C)
pH 7, half-life = 1.569 years
pH 8, half-life = 57.292 days - Executive summary:
Results from the EPI-Suite v4.0 fugacity Level III distribution model (US EPA 2009) show that because of its low water solubility, the test substance is not expected to partition to the water compartment (see Section 4.2.3). However, abiotic degradation of any trace amounts of the test substance which may be present in aquatic environments is unlikely to occur at a significant rate based on modeled data. The HYDROWIN model, a subroutine within the US EPA EPI-Suite v4.0 computer program, estimates a hydrolysis half-life for the test substance 1.569 years at pH 7 (25°C) and 57.292 days at pH 8 (25°C).
Reference
Description of key information
Results from the EPI-Suite v4.0 fugacity Level III distribution model (US EPA 2009) show that because of its low water solubility, the test substance is not expected to partition to the water compartment (see Section 4.2.3). However, abiotic degradation of any trace amounts of the test substance which may be present in aquatic environments is unlikely to occur at a significant rate based on modeled data. The HYDROWIN model, a subroutine within the US EPA EPI-Suite v4.0 computer program, estimates a hydrolysis half-life for the test substance 1.569 years at pH 7 (25°C) and 57.292 days at pH 8 (25°C).
Hydrolysis will not significantly contribute to the removal of the test substance from the environment.
The hydrolysis half-life (1.569 years) was calculated at pH 7. For ph8, the half-life was calculated as 57.292 days.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1.569 yr
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
