Registration Dossier

Administrative data

Description of key information

Tke key studies for skin and eye irritation found the undiluted test material not irritating to the skin or eye of rabbits (Safepharm Laboratories, 1995; rel 1).

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Reliable studies on several different formulations consistently demonstrate a low degree of irritation, well below the threshold for classification.

Nor do these ammonium salts exhibit the extreme pHs of other salts.

Justification for classification or non-classification

Based on the available data and knowledge of pH of the ammonium salts, it is proposed that these salts do not required classification for skin or eye irritation/corrosion.