Registration Dossier
Registration Dossier
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EC number: 248-660-0 | CAS number: 27794-93-0
Endpoint summary
Administrative data
Description of key information
Additional information
ATMP and its potassium salt will fully dissociate in an aqueous solution and will behave no differently to the parent acid and the potassium counter ion, at their equivalent concentrations in solution. It is not expected that the potassium counter ions will contribute significantly to the overall toxicity of their ATMP salts. Therefore, the impact on aquatic organisms will be dominated by the affects of the ATMP acid (CAS 6419 -19 -8).
In a short-term test with fish a 96-h LC50 value of 160 mg/L has been determined for the effects of ATMP active acid on mortality of Oncorhynchus mykiss. This value is equivalent to 260 mg/L ATMP-xK (CAS 27794-93-0, where x = 5). In a long-term test a 60-day NOEC of 23 mg/L has been determined for the effects of ATMP active acid on growth of O. mykiss fry. This value is equivalent to 40 mg/L ATMP-xK (CAS 27794 -93 -0, where x=5).
In a short-term test with invertebrates a 48-h EC50 value of 297 mg/L (as active acid) has been determined for the effects of ATMP acid on mobility of Daphnia magna. A 48 h LC50 value of 94 mg/L (as active acid) has been determined for the effects of ATMP acid on mortality of the marine invertebrate Acartia tonsa. These values are respectively equivalent to 297 * 1.64 = 485 mg/L and 94 * 1.64 = 155 mg/L ATMP-xK, (CAS 27794-93-0, where x = 5). In a long-term test with D. magnaa 28-day NOEC of 25 mg/L has been determined for the effects of ATMP acid on adult survival and reproduction. This value is equivalent to a 28 d NOEC value of 25 * 1.64 = 40 mg/L ATMP-xK (CAS 27794-93-0, where x = 5).
Studies conducted with algae cannot be used to assess the intrinsic hazard properties of phosphonates due to chelating effects of the substance on essential nutrients.
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