Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Workers - Hazard via inhalation route

Systemic effects

Long term exposure
Hazard assessment conclusion:
hazard unknown (no further information necessary)
Acute/short term exposure
Hazard assessment conclusion:
insufficient hazard data available (further information necessary)
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
hazard unknown (no further information necessary)
Acute/short term exposure
Hazard assessment conclusion:
hazard unknown (no further information necessary)
DNEL related information

Workers - Hazard via dermal route

Systemic effects

Long term exposure
Hazard assessment conclusion:
hazard unknown (no further information necessary)
Acute/short term exposure
Hazard assessment conclusion:
hazard unknown (no further information necessary)
DNEL related information

Local effects

Long term exposure
Hazard assessment conclusion:
other toxicological threshold
Value:
28.58 µg/cm²
Most sensitive endpoint:
sensitisation (skin)
DNEL related information
DNEL derivation method:
ECHA REACH Guidance
Overall assessment factor (AF):
50
Dose descriptor:
other: EC3
AF for dose response relationship:
1
Justification:
default AF; clear EC3
AF for differences in duration of exposure:
1
Justification:
not relevant; local effect
AF for interspecies differences (allometric scaling):
1
Justification:
see overall interspecies AF
AF for other interspecies differences:
10
Justification:
proposed AF in ECHA guidance
AF for intraspecies differences:
5
Justification:
default AF for workers
AF for the quality of the whole database:
1
Justification:
default AF
AF for remaining uncertainties:
1
Justification:
Vehicle/matrix effects (not relevant); moderate potency (i.e. EC3 >2% w/v)
Acute/short term exposure
Hazard assessment conclusion:
other toxicological threshold
Value:
28.58 µg/cm²
Most sensitive endpoint:
sensitisation (skin)
DNEL related information
DNEL derivation method:
ECHA REACH Guidance
Overall assessment factor (AF):
50
Dose descriptor starting point:
other: EC3
AF for dose response relationship:
1
Justification:
default AF; clear EC3
AF for interspecies differences (allometric scaling):
1
Justification:
see overall interspecies AF
AF for other interspecies differences:
10
Justification:
proposed AF in ECHA guidance
AF for intraspecies differences:
5
Justification:
default AF for workers
AF for the quality of the whole database:
1
Justification:
default AF
AF for remaining uncertainties:
1
Justification:
Vehicle/matrix effects (not relevant); moderate potency (i.e. EC3 >2% w/v)

Workers - Hazard for the eyes

Local effects

Hazard assessment conclusion:
no hazard identified

Additional information - workers

General Population - Hazard via inhalation route

Systemic effects

Acute/short term exposure
DNEL related information

Local effects

Acute/short term exposure
DNEL related information

General Population - Hazard via dermal route

Systemic effects

Acute/short term exposure
DNEL related information

General Population - Hazard via oral route

Systemic effects

Acute/short term exposure
DNEL related information

General Population - Hazard for the eyes

Additional information - General Population

Consumers are not exposed to unreacted p-PP