tetrasodium 4-{4-[(9,10-dioxo-4-{[4-(2-sulfophenoxy)phenyl]amino}-9,10-dihydroanthracen-1-yl)amino]phenoxy}benzene-1-sulfonate 4-{4-[(9,10-dioxo-4-{[4-(4-sulfophenoxy)phenyl]amino}-9,10-dihydroanthracen-1-yl)amino]phenoxy}benzene-1-sulfonate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Identification: FAT 21030/E TE
Appearance: Dark green powder

Water solubility:

7.7 g/L

Temp.:

20 °C

Remarks on result:

other: The water solubility cs of the test item at a temperature of 20°C was determined to (without correction for the purity): cs = 7.70 g/L

Details on results:

Flask-Method
Water solubility of the test item in 4 experiments including a blank.
Average experiments: 7.70 g/L
The recovery of 99.8 % indicated a sufficient accuracy of the analytical method.

Preliminary Visual Estimation of the Water Solubility

 

Table: Appearance of the test mixtures

Amount of the test item in mg	Total volume in ml	Appearance of mixture
100	10	Undissolved
	20	Dissolved

The preliminary visual experiments showed that the water solubility of the test item is >5 g/l.

Flask-Method

Water solubility of the test item – experiments A to D

 

Experiment		A		B		C		D(blank)
Amount of test item (mg)		1000		1000		1000		---
Stirring time at 30 °C (h)		24		48		72		72
Aliquot:		0.025/10		0.025/10		0.025/10
Measured concentration (µg/ml)		18.45		19.89		19.40		n.d.
Water solubility (g/l)		7.38		7.95		7.76		---

Average experiments A to C: 7.70 g/l

 

Table: Standard addition for recheck:  

Standard	Measured concentration (µg/ml)	% Recovery
Sample C + 21.28 µg test item	40.59	99.8

The recovery of 99.8 % indicates a sufficient accuracy of the analytical method.

Conclusions:

The water solubility of the test item at a temperature of 20 °C was determined to be 7.70 g/L.

Executive summary:

FAT 21030/E TE was evaluated for water solubility according to OECD Guideline 105. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 7.70 g/L.

Description of key information

FAT 21030/E TE was evaluated for water solubility according to OECD Guideline 105. Flask method was used for this purpose. Based on the findings of the study, the water solubility of the test item at a temperature of 20 °C was determined to be 7.70 g/L.

Key value for chemical safety assessment

Water solubility:

7.7 g/L

at the temperature of:

20 °C