Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 207-529-8 | CAS number: 479-27-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- The substance is dissolved in a mineral medium, inoculated with a mixed population of aquatic microorganisms and incubated for 28 days under aerobic conditions in the dark at 20 ± 1 ° C. The biodegradability of the test substance during the time determined by the decrease in the concentration of dissolved oxygen in the test concentrations.
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source: Expiration of a laboratory activated sludge plant is operated with wastewater of southern Wupper Association.
- Treatment given: coarse filtration through fluted filter
- Direct weighing: 2.7 mg/L
- Concentration in the reaction mixture: 5 mL/L
- Preparation / conditioning: Ventilation for 7 days - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2.7 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- 2.7 mg/L of the test item and 2.0 mg/L of the reference substance was stirred in a closed bottle and inoculated at a constant temperature (20 ± 1 °C) for up 28 days under aerobic conditions in the dark.
Determine the concentration of dissolved oxygen for control purposes; the value should be about 9 mg/L at 20 °C.
Assemble a sufficient number of closed bottles, including inoculum blanks, to allow at least duplicate measurements of oxygen consumption to be made at the desired test intervals, for example, after 0, 7, 14, 21 and 28 days. To ensure being able to identify the 10-day window, more bottles may be required. - Reference substance:
- aniline
- Remarks:
- at least 99.5 %
- Parameter:
- % degradation (O2 consumption)
- Value:
- 2
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 1
- Sampling time:
- 28 d
- Results with reference substance:
- Kinetic of reference substance (% Degradation):
59 after 7 days
75 after 14 days
81 after 21 days
85 after 28 days - Validity criteria fulfilled:
- yes
- Remarks:
- (- Ready biodegradability of reference compound 75 % within 14 days. - In the toxicity control degradation rates > 25 % within 14 days.)
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Within 28 days, a degradation rate of 1 % was determined. 1,8-naphthylenediamine is considered to be "Not Readily Biodegradable". The reference compound aniline showed 75 % degradation after 14 days.
- Executive summary:
To test for its biodegradability potential, 1,8-naphthylenediamine was incubated for 28 days in continuously stirred in closed bottle in the dark with an inoculum originally collected form a local, prodominantly municipal wastewater trearment plant.
The incubation temperature was 20 ± 1 °C. Determine the concentration of dissolved oxygen for control purposes; the value should be about 9 mg/L at 20 °C. Assemble a sufficient number of closed bottles, including inoculum blanks, to allow at least duplicate measurements of oxygen consumption to be made at the desired test intervals, for example, after 0, 7, 14, 21 and 28 days. The 28-day degradation was 1 % and for the reference compound the biodegradation was 85 %. In conclusion the substance is not readily biodegradable.
Reference
Description of key information
Within 28 days, a degradation rate of 1 % was determined. The test item is considered to be "Not Readily Biodegradable". The reference compound aniline showed 75 % degradation after 14 days.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.