Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 254-879-2 | CAS number: 40306-75-0
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 98-42-0
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling Database
- Principles of method if other than guideline:
- Skin irritation (Severe vs mild). Multicase model.
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-amino-4-methoxybenzenesulphonic acid
- EC Number:
- 202-667-5
- EC Name:
- 3-amino-4-methoxybenzenesulphonic acid
- Cas Number:
- 98-42-0
- Molecular formula:
- C7H9NO4S
- IUPAC Name:
- 3-amino-4-methoxybenzenesulfonic acid
Constituent 1
Test animals
- Species:
- other: no data
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Duration of treatment / exposure:
- no data
- Observation period:
- no data
- Number of animals:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Reversibility:
- no data
- Remarks on result:
- other: Not irritant
Applicant's summary and conclusion
- Conclusions:
- 3-amino-4-methoxybenzenesulphonic acid is estimated to be non irritating to skin
- Executive summary:
3-amino-4-methoxybenzenesulphonic acid is estimated to be non irritating to skin
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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