Registration Dossier
Registration Dossier
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EC number: 274-713-2 | CAS number: 70643-20-8
Endpoint summary
Administrative data
Description of key information
For the purpose of REACH registration, read across with the analogue substance 2-(2,4-diaminophenoxy)ethanol dihydrochloride appears appropriate. Under the experimental conditions, the LD50 of the test item was close to 1000 mg/kg bw since a single dose of 1000 mg/kg induced death in 1/5 male and 3/5 female rats. Based on the available data for 2-(2,4-diaminophenoxy)ethanol dihydrochloride the acute oral toxicity of 2-(2,4-diaminophenoxy)ethanol sulphate is calculated to be 1104 mg/kg bw.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 104 mg/kg bw
Additional information
Justification for classification or non-classification
For the purpose of REACH registration, read across with the analogue substance 2-(2,4-diaminophenoxy)ethanol dihydrochloride appears appropriate. The acute oral toxicity of the substance was assessed according to OECD 401 incompliance to GLP. Under the experimental conditions, the LD50 of the test item was close to 1000 mg/kg bw. Based on the available data for 2-(2,4-diaminophenoxy)ethanol dihydrochloride the acute oral toxicity of 2-(2,4-diaminophenoxy)ethanol sulphate is calculated to be 1104 mg/kg bw. In accordance with Directive 67/548 and Regulation (EC) No 1272/2008 the substance is classified as harmful if swallowed.
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