Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
1-Chlor-2-methyl-3-nitrobenzol (2-Chlor-6-nitrotoluol) BUA Stoffbericht 61
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1991
Bibliographic source:
VCH Verlagsgesellschaft mbH, Weinheim, ISBN 3-527-28427-3
Reference Type:
study report
Title:
Unnamed
Year:
1983

Materials and methods

Test guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit

Test system

Type of coverage:
semiocclusive
Duration of treatment / exposure:
4 h
Observation period:
72 h

Results and discussion

Any other information on results incl. tables

The investigation showed slight irritation in the form of mild to significant erythema, in individual cases visible even after 72 hours,

but no edema.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU