Registration Dossier

Administrative data

Endpoint:
developmental toxicity
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Authoritative data base
Title:
Danish QSAR study for CAS No.: 59690-88-9
Author:
Danish EPA Model
Year:
2012
Bibliographic source:
QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:- Commercial

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: modelling database
Principles of method if other than guideline:
Teratogenicity (human). Multicase model.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material : (3-aminophenyl)uronium chloride

Test animals

Species:
other: human
Strain:
not specified

Administration / exposure

Type of inhalation exposure (if applicable):
not specified
Vehicle:
not specified

Results and discussion

Results: maternal animals

Effect levels (maternal animals)

Basis for effect level:
other: effect type not specified

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Applicant's summary and conclusion

Conclusions:
Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.
Executive summary:

Teratogenicity of (3-aminophenyl)uronium chloride is estimated to give negative result.