Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short term toxicity to fish

Using the weight of evidence approach, the available data indicates that (3-aminophenyl)uronium chloride is unlikely to cause short term aquatic toxicity to fish within the concentration ranges mentioned in the various end points.

The summary of the data used as weight of evidence is mentioned below

S. No

End point

Species

Effect

Source

1

LC50 = 4437.716

Not specified

Mortality

ECOSAR

2

LC50 = 234.657

Oncorhynchus mykiss

Mortality

QSAR

3

LC50 = 209.419

Pimephales promelas

Mortality

QSAR

Short term toxicity to aquatic invertebrates

LC50 value of (3-aminophenyl)uronium chloride in Daphnia magna after 48 h is estimated to be 13686.932 mg/L. Thus, it can be concluded that (3-aminophenyl)uronium chloride is unlikely to cause short term toxicity to aquatic invertebrate within the concentration range mentioned in this end point

Toxicity to aquatic algae and cyanobacteria

EC50 value of (3-aminophenyl)uronium chloride in aquatic algae Selenastrum capricornutum is estimated to be 818.5665 mg/L. Thus, it can be concluded that (3-aminophenyl)uronium chloride is unlikely to cause short term toxicity to aquatic invertebrate within the concentration range mentioned in this end point.

Toxicity to micro-organisms

EC50 value of (3-aminophenyl)uronium chloride in Tetrahymena pyriformis after 46 h is estimated to be 320.6099 mg/L on the basis of the effect of growth inhibition.