Registration Dossier
Registration Dossier
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EC number: 202-662-8 | CAS number: 98-37-3
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 98-37-3
- Author:
- Danish EPA Model
- Year:
- 2 012
- Bibliographic source:
- QSAR predictions by Danish Environmental Protection Agency (EPA)model powered by OASIS database:-DK-EPA
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: modelling database
- Principles of method if other than guideline:
- Skin irritation (Severe vs mild) Multicase model.
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-amino-4-hydroxybenzenesulphonic acid
- EC Number:
- 202-662-8
- EC Name:
- 3-amino-4-hydroxybenzenesulphonic acid
- Cas Number:
- 98-37-3
- Molecular formula:
- C6H7NO4S
- IUPAC Name:
- 3-amino-4-hydroxybenzenesulphonic acid
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material : 3-amino-4-hydroxybenzenesulphonic acid
-Substance type-organic
-physical state-crystalline solid.
Constituent 1
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Remarks on result:
- other: Eqivocal
Applicant's summary and conclusion
- Interpretation of results:
- other: Eqivocal
- Remarks:
- Criteria used for interpretation of results: EU
- Conclusions:
- Skin irritation of 3-amino-4-hydroxybenzenesulphonic acid is estimated to give equivocal result
- Executive summary:
Skin irritation of 3-amino-4-hydroxybenzenesulphonic acid is estimated to give equivocal result. However, if one considers the pH of the chemical, the chemical is highly acidic and hence expected to be a positive skin irritant
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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