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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

Link to relevant study record(s)

Description of key information

Three studies were carried out to assess the biodegradation properties of the test item. In the key study, the ready biodegradability of the test item was determined with a non adapted activated sludge in the Manometric Respirometry Test for a period of 28 days. The study was conducted according to OECD guideline 301 F. 5-Ethyl-2-methylpyridine showed a mean biodegradation rate of 2% (ThOD NH4) and 1.5% (ThOD NO3) and is considered to be not readily biodegradable.


In the supporting study ready biodegradation was tested according to OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test). The test item was determined ready biodegradable, but failing the 10-day window. In a supporting study according to OECD 302 B (Zahn-Wellens test) the test item showed inherent biodegradation, with 98.7 % degradation in 21 days.

Key value for chemical safety assessment

Biodegradation in water:
not biodegradable

Additional information

Key study - OECD Guideline 301 F


The ready biodegradability of the test item was determined with a non adapted activated sludge in the Manometric Respirometry Test for a period of 28 days. The study was conducted according to OECD guideline 301 F. 5-Ethyl-2-methylpyridine showed a mean biodegradation rate of 2% (ThOD NH4) and 1.5% (ThOD NO3) and is considered to be not readily biodegradable based on  ThODNH4 and ThODNO3.


Supporting study - OECD Guideline 301 E


In the key study biodegradation was assessed according to OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test). Test substance concentrations of 25.7 and 18.9 mg DOC/l were tested over a period of 28 days. The test item biodegraded 77 % within 28 days, but failed the 10 -day window. The reference compound Aniline was degraded by 93 % within 14 days. In conclusion, the test item was considered readily biodegradable, but failing the 10-day window under the conditions of the test.


 


Supporting study - OECD Guideline 302 B


In a supporting study biodegradation was assessed according to OECD Guideline 302 B (Zahn-Wellens test). The test item biodegraded 98.7 % within 21 days. In conclusion, the substance was determined inherently biodegradable under the conditions of this test.