Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-402-6 | CAS number: 106-48-9
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 1989
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data from WHO report on chlorophenols (collective views of an international group of experts).
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Chlorophenols other than pentachlorphenol (environmental health criteria 93)
- Author:
- EHC
- Year:
- 1 989
- Bibliographic source:
- http://www.inchem.org
- Reference Type:
- publication
- Title:
- The tumor-promoting action of phenol and related compounds for mouse skin.
- Author:
- Boutwell RK, Bosch DK
- Year:
- 1 959
- Bibliographic source:
- Cancer Res. 19:413-424.
Materials and methods
- Type of study / information:
- Tumour promotion in mice.
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-chlorophenol / 108-43-0
- IUPAC Name:
- 3-chlorophenol / 108-43-0
- Reference substance name:
- 2-chlorophenol / 95-57-8
- IUPAC Name:
- 2-chlorophenol / 95-57-8
Constituent 1
Constituent 2
Results and discussion
Any other information on results incl. tables
The authors reported that the 2-chlorophenol, 3-chlorophenol, 2,4-Dichlorophenol, and 2,4,5-T3CP all had a tumour-promoting action similar to that of phenol, while 2,4,6-T3CP did not have any effect on tumour promotion.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
