Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-402-6 | CAS number: 106-48-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed database
Data source
Reference
- Reference Type:
- publication
- Title:
- pH-Metric Log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values"
- Author:
- B. Slater, A. McCormack, A. Avdeef and J.E.A. Comer
- Year:
- 1 994
- Bibliographic source:
- B. Slater, A. McCormack, A. Avdeef and J.E.A. Comer, "pH-Metric Log P. 4. Comparison of partition coefficients determined by HPLC and potentiometric methods to literature values", J. Pharm. Sci. 83(9), 1280-1283 (1994) as cited in LOGKOW database
- Report date:
- 2014
Materials and methods
- Principles of method if other than guideline:
- Secondary literature source no data about the guideline was available.
- GLP compliance:
- not specified
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 4-chlorophenol
- EC Number:
- 203-402-6
- EC Name:
- 4-chlorophenol
- Cas Number:
- 106-48-9
- Molecular formula:
- C6H5ClO
- IUPAC Name:
- 4-chlorophenol
- Test material form:
- solid: crystalline
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.41
- Remarks on result:
- other: No data about pH value and temperatutre were given
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
