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EC number: 700-801-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Jan-Jun 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: study performed according to OECD guideline and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Bottom product of propylene oxide and styrene production
- IUPAC Name:
- Bottom product of propylene oxide and styrene production
- Details on test material:
- - Name of test material (as cited in study report): KORE grade V
- Substance type: UVCB
- Physical state: Brown viscous liquid
- Stability under test conditions: months
- Storage condition of test material: room temperature
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Prior to use a sample of activated sludge from the sewage plant at Taunusstein-Bleidenstadt was washed twice with mineral nutrient solution of the CO2-Evolution-Test to eliminate organic components and carbonates from the sludge. After resolution with mineral nutrient medium the sludge was aerated by means of compressed humidified air for about four hours. Before use as inoculum for the CO2-Evolution-Test the sludge was homogenised in a "Waring Blender" at low speed for 2 minutes and then filtered through a cotton filter previously carefully rinsed with deionised water. The filtrate was used as inoculum (1% of the final volume of the test solution) on the same day of preparation.
- Duration of test (contact time):
- ca. 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 103.3 mg/L
- Based on:
- test mat.
- Initial conc.:
- 104.4 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: as mentioned in the guideline
- Additional substrate: none
- Solubilising agent: none
- Test temperature: values were in the range of 19.6 to 21.3 °C (mean 20.1°C)
- pH: 7.4 ± 0.2 at t0
- pH adjusted: no
- Aeration of dilution water: the aeration rate of the test system was controlled at 4 L/h
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: ≈5-litre amber carboys served as test vessels. They were closed with stoppers with tubing for gas inlet and outlet (gas exit line)
- Number of culture flasks/concentration: two vessel with the test item, one vessel with sodiumbenzoate (control item), one toxicity control
- Method used to create aerobic conditions: aeration
SAMPLING
- Sampling frequency: Titrations were performed at t3d, t5d, t10d, t14d, t20d, t28d, and t29d
- Sample storage before analysis: data not available
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: yes
STATISTICAL METHODS: not applicable
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 20 mg TOC/L
Results and discussion
% Degradation
- Parameter:
- other: O2 uptake in the test solutions
- Value:
- 50.8
- Sampling time:
- 28 d
- Remarks on result:
- other: mean value
- Details on results:
- The degradation process was followed by the oxygen uptake in the test solutions using two test solutions of the test item. With respect to the theoretical oxygen demand (ThOD) of the test item and the measured BOD of the test solutions a degradation value of 53% of the test item was measured within the first test solution using 103.3 mg/L of the test item after 28 days of incubation. 48.6% degradation was observed in the second test solution with 104.0 mg/L test item.
The calculated mean degradation value of the test item was 50.8 %.
BOD5 / COD results
- Results with reference substance:
- The control item sodium benzoate was degraded 88 %, the "10-days-window" being met within 5 days (68 %).
Any other information on results incl. tables
Degradation of the Test Item in the 1stTest Solution, 103.3 mg/L
Time (d) |
Values read on the Display of the Respirometer (mg O2/L)1) |
% Degradation |
||
Blank 1 |
Blank 22) |
Test Item |
||
0.0 |
0 |
0 |
0 |
0.0 |
1.0 |
0 |
0 |
0 |
0.0 |
2.0 |
0 |
0 |
0 |
0.0 |
3.0 |
0 |
0 |
85 |
9.3 |
3.9 |
1 |
0 |
159 |
17.4 |
4.9 |
4 |
0 |
242 |
26.2 |
5.9 |
6 |
0 |
270 |
29.0 |
7.0 |
8 |
0 |
295 |
31.6 |
7.9 |
10 |
0 |
313 |
33.3 |
8.8 |
11 |
0 |
326 |
34.6 |
10.1 |
13 |
0 |
338 |
35.7 |
11.0 |
14 |
0 |
354 |
37.4 |
12.0 |
15 |
0 |
367 |
38.7 |
12.9 |
16 |
0 |
379 |
39.9 |
13.9 |
18 |
0 |
394 |
41.3 |
14.9 |
19 |
0 |
408 |
42.8 |
15.9 |
20 |
0 |
424 |
44.4 |
16.8 |
21 |
0 |
434 |
45.4 |
17.9 |
23 |
0 |
446 |
46.5 |
19.0 |
23 |
0 |
458 |
47.8 |
20.0 |
24 |
0 |
465 |
48.5 |
20.9 |
25 |
0 |
472 |
49.2 |
22.0 |
28 |
0 |
479 |
49.6 |
22.9 |
28 |
0 |
485 |
50.3 |
24.1 |
28 |
0 |
494 |
51.2 |
25.0 |
29 |
0 |
497 |
51.5 |
25.9 |
30 |
0 |
504 |
52.1 |
27.0 |
31 |
0 |
508 |
52.5 |
28.0 |
33 |
0 |
517 |
53.2 |
1)The indicated values are multiplied by factor 0.25 which is valid for the 1000 mL of volume.
2)not considered as there was an equipment error.
Degradation of the Test Item in the 2ndTest Solution, 104.0 mg/L
Time (d) |
Values read on the Display of the Respirometer (mg O2/L)1) |
% Degradation |
||
Blank 1 |
Blank 22) |
Test Item |
||
0.0 |
0 |
0 |
0 |
0.0 |
1.0 |
0 |
0 |
0 |
0.0 |
2.0 |
0 |
0 |
35 |
3.8 |
3.0 |
0 |
0 |
103 |
11.3 |
3.9 |
1 |
0 |
184 |
20.0 |
4.9 |
4 |
0 |
245 |
26.3 |
5.9 |
6 |
0 |
271 |
28.9 |
7.0 |
8 |
0 |
288 |
30.6 |
7.9 |
10 |
0 |
296 |
31.2 |
8.8 |
11 |
0 |
306 |
32.2 |
10.1 |
13 |
0 |
324 |
34.0 |
11.0 |
14 |
0 |
336 |
35.2 |
12.0 |
15 |
0 |
350 |
36.6 |
12.9 |
16 |
0 |
362 |
37.8 |
13.9 |
18 |
0 |
374 |
38.9 |
14.9 |
19 |
0 |
384 |
39.9 |
15.9 |
20 |
0 |
394 |
40.9 |
16.8 |
21 |
0 |
402 |
41.6 |
17.9 |
23 |
0 |
411 |
42.4 |
19.0 |
23 |
0 |
420 |
43.4 |
20.0 |
24 |
0 |
426 |
43.9 |
20.9 |
25 |
0 |
433 |
44.6 |
22.0 |
28 |
0 |
442 |
45.2 |
22.9 |
28 |
0 |
446 |
45.7 |
24.1 |
28 |
0 |
454 |
46.5 |
25.0 |
29 |
0 |
459 |
47.0 |
25.9 |
30 |
0 |
465 |
47.5 |
27.0 |
31 |
0 |
469 |
47.8 |
28.0 |
33 |
0 |
478 |
48.6 |
1)The indicated values are multiplied by factor 0.25 which is valid for the 1000 mL of volume.
2)not considered as there was an equipment error.
Degradation of the Toxicity Control
Time (d) |
Values read on the Display of the Respirometer (mg O2/L)2) |
% Degradation1) |
||
Blank 1 |
Blank 23) |
Toxicity Control |
||
0.0 |
0 |
0 |
0 |
0.0 |
1.0 |
0 |
0 |
62 |
3.8 |
2.0 |
0 |
0 |
258 |
15.6 |
3.0 |
0 |
0 |
322 |
19.5 |
3.9 |
1 |
0 |
383 |
23.2 |
4.9 |
4 |
0 |
477 |
28.9 |
5.9 |
6 |
0 |
609 |
36.8 |
7.0 |
8 |
0 |
633 |
38.2 |
7.9 |
10 |
0 |
643 |
38.7 |
8.8 |
11 |
0 |
661 |
39.7 |
10.1 |
13 |
0 |
688 |
41.3 |
11.0 |
14 |
0 |
691 |
41.5 |
12.0 |
15 |
0 |
712 |
42.7 |
12.9 |
16 |
0 |
727 |
43.6 |
13.9 |
18 |
0 |
728 |
43.6 |
14.9 |
19 |
0 |
731 |
43.7 |
15.9 |
20 |
0 |
739 |
44.2 |
16.8 |
21 |
0 |
741 |
44.3 |
17.9 |
23 |
0 |
743 |
44.3 |
19.0 |
23 |
0 |
744 |
44.4 |
20.0 |
24 |
0 |
745 |
44.4 |
20.9 |
25 |
0 |
763 |
45.5 |
22.0 |
28 |
0 |
800 |
47.6 |
22.9 |
28 |
0 |
815 |
48.5 |
24.1 |
28 |
0 |
822 |
49.0 |
25.0 |
29 |
0 |
836 |
49.8 |
25.9 |
30 |
0 |
845 |
50.3 |
27.0 |
31 |
0 |
885 |
52.7 |
28.0 |
33 |
0 |
890 |
52.9 |
1)The basis for the biodegradation is the sum of ThODs of both the test item and sodium benzoate.
2) The indicated values are multiplied by factor 0.5 which is valid for the 500 mL of volume.
3)not considered as there was an equipment error.
With respect to the theoretical oxygen demand (ThOD) of the test item and the measured BOD of the test solutions a degradation value of 53% of the test item was measured within the first test solution using 103.3 mg/L of the test item after 28 days of incubation. 48.6% degradation was observed in the second test solution with 104.0 mg/L test item.The toxicity control showed >25% degradation within 14 days based on total ThOD, therefore the test substance is not considered to be inhibitory according to the OECD test guidelines 301.Regarding the results obtained within this study the test item should be considered "not readily biodegradable". The control item sodium benzoate was degraded 98% within 28d. The threshold of³60% was met within 5d (60.8%) of incubation. Therefore, the test is considered valid. An abiotic degradation can be excluded.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- The test substance is not considered to be inhibitory.
The test item should be considered "not readily biodegradable" - Executive summary:
”KORE grade V“was tested for biodegradability according to ‘Manometric Respirometry Test' (OECD Guideline 301F).The degradation process was followed by the oxygen uptake in the test solutions using two test solutions of the test item. With respect to the theoretical oxygen demand (ThOD) of the test item and the measured BOD of the test solutions a degradation value of 53% of the test item was measured within the first test solution using 103.3 mg/L of the test item after 28 days of incubation. 48.6% degradation was observed in the second test solution with 104.0 mg/L test item.The toxicity control showed >25% degradation within 14 days based on total ThOD, therefore the test substance is not considered to be inhibitory according to the OECD test guidelines 301.Regarding the results obtained within this study the test item should be considered "not readily biodegradable". The control item sodium benzoate was degraded 98% within 28d. The threshold of³60% was met within 5d (60.8%) of incubation. Therefore, the test is considered valid. An abiotic degradation can be excluded.
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