Registration Dossier
Registration Dossier
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EC number: 241-475-6 | CAS number: 17462-58-7
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish:
Parent compound: 96-h LC50 = ca. 46.4 mg/L (BASF AG, 1999)
Hydrolysis product sec-butanol: 96 -h LC50 = 3670 mg/L (OECD, 2002)
Hydrolysis product HCl: 96 -h LC50 = 4.92 mg/L (OECD, 2002)
Short-term toxicity to aquatic invertebrates:
Parent compound: no data
Hydrolysis product sec-butanol: 48 -h EC50 = 4227 mg/L (D. magna) (OECD, 2002)
Hydrolysis product HCl: 48 -h EC50 = 0.492 mg/L (OECD, 2002)
Long-term toxicity to aquatic invertebrates:
No relevant and reliable data available.
Growth inhibition to aquatic algae:
Parent compound: no data
Hydrolysis product sec-butanol (weight-of-evidence): EC50 > 100 mg/L
Hydrolysis product HCl: 72 -h EC50 = 0.492 mg/L; NOEC = 0.097 mg/L (OECD, 2002)
Toxicity to microorganisms:
Parent compound: no data
Analogous compound isopropyl chloroformate: Activated sludge respiration inhibition: 30 -min EC0 = 2527 mg/L (BASF, 1983); covering also the hydrolysis products isopropanol and HCl
Hydrolysis product sec-butanol: Pseudomonas putida 16 -h EC0 = ca. 500 mg/L (OECD, 2002)
An inhibition of the degradation activity of activated sludge is not expected when introduced to biological treatment plants in appropriate low concentrations.
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