Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 939-017-1 | CAS number: 1469982-94-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- Experimental Starting Date: 23 April 2012 Experimental Completion Date: 01 June 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2012
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- The water solubility was calculated using WSKOW v1.42 (Sept 2010), © 2000 U.S. Environmental Protection Agency.
- GLP compliance:
- yes
- Type of method:
- flask method
Test material
- Reference substance name:
- Isostearamide DEA
- IUPAC Name:
- Isostearamide DEA
- Details on test material:
- Identification: Isostearamide DEA
Description: Amber colored liquid
Batch: OE11124 (6/202593/00)
Purity: 100 %
Expiry / Retest Date: Not supplied
Storage Conditions: Room temperature in the dark
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 0 g/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Using WSKOW v1.42 (Sept 2010), © 2000 U.S. Environmental Protection Agency, the water solubility was calculated to be 5.5 x 10-5 g/L at 25 °C.
- Details on results:
- The results indicated that the test item forms stable emulsions in water, and therefore, its water availability is loading rate dependent. Attempts were made to clean up the samples using centrifugation and filtration; however, the attempts were unsuccessful. The findings indicated that a limit of (self-) emulsifying potential was attained between 50.1 and 75.1 % w/w.
Using WSKOW v1.42 (Sept 2010), © 2000 U.S. Environmental Protection Agency, the water solubility was calculated to be 5.5 x 10-5 g/L at 25 °C.
Any other information on results incl. tables
Results
Preliminary Test
The loading rate, observations recorded following equilibration and the pH for each solution are shown in the following table:
Table 3.10
Sample Number |
Loading Rate (% w/w) |
Observations |
Solution pH |
P1 |
0.108 |
Clear, colourless liquid with excess test item present. |
6.5 |
P2 |
1.02 |
White, opaque liquid with excess test item present. |
8.4 |
Overall result: Attempts were made to clean up the samples using centrifugation and filtration. However, the attempts were unsuccessful. Therefore, it was concluded that the test item forms stable emulsions in water, and thus, the “water solubility” would be loading rate dependent.
Definitive Test
The loading rate, observations recorded following equilibration and the pH for each solution are shown in the following table:
Table 3.11
Sample Number |
Loading Rate |
Observations |
Solution pH |
1 |
10.5 |
Approximately 5 % excess visible test item separate from a white, opaque, non-viscous liquid. |
7.5 |
2 |
24.9 |
Approximately 15 % excess visible test item separate from a creamy, opaque, non-viscous liquid. |
9.0 |
3 |
50.1 |
Creamy liquid, non-viscous, uniform emulsion with no excess test item visible. |
8.8 |
4 |
75.1 |
Approximately 60 % excess visible test item separate from a creamy, opaque, non-viscous liquid. |
* |
5 |
88.8 |
Amber coloured, slightly viscous liquid. |
* |
*Not possible, due to the nature of the sample.
Overall results: The results of the preliminary and definitive tests indicate that the test item forms stable emulsions in water, and therefore, the “water solubility” is loading rate dependent.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The results indicated that the test item forms stable emulsions in water, and therefore, its water availability is loading rate dependent. Attempts were made to clean up the samples using centrifugation and filtration; however, the attempts were unsuccessful. The findings indicated that a limit of (self-) emulsifying potential was attained between 50.1 and 75.1 % w/w.
Using WSKOW v1.42 (Sept 2010), © 2000 U.S. Environmental Protection Agency, the water solubility was calculated to be 5.5 x 10-5 g/L at 25 °C. - Executive summary:
- The determination was carried out by
visual assessment, using a flask method, based on Method A6 Water
Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and
Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Additionally, the water solubility was calculated using WSKOW v1.42 (Sept 2010), © 2000 U.S. Environmental Protection Agency.
Discussion
The standard EC A6/ OECD 105 procedures were not applicable to this test item due to the high indeterminable saturation levels produced. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guideline. No analysis could be performed due to the high solubility producing unfilterable mixtures and thus the water solubility was estimated based on visual inspection.
As the test item was noted to form stable emulsions in water (as opposed to true solutions), it was considered that evaluation of emulsification potential at differing loading rates would be more meaningful with respect to environmental effect.
Conclusion
The results indicated that the test item forms stable emulsions in water, and therefore, its water availability is loading rate dependent. Attempts were made to clean up the samples using centrifugation and filtration; however, the attempts were unsuccessful. The findings indicated that a limit of (self-) emulsifying potential was attained between 50.1 and 75.1 % w/w.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.