Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: QSAR report
- Title:
- Unnamed
- Year:
- 2 022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR prediction models
- Deviations:
- no
- GLP compliance:
- no
Test material
- Reference substance name:
- tributyl(ethyl)phosphonium 4-methylbenzenesulfonate
- Cas Number:
- 119520-10-4
- Molecular formula:
- C21H39O3PS
- IUPAC Name:
- tributyl(ethyl)phosphonium 4-methylbenzenesulfonate
Constituent 1
Results and discussion
Test results
- Key result
- Species / strain:
- other: E. coli WP2 uvr A, S. typhimurium TA 100, S. typhimurium TA 1535, S. typhimurium TA 1535, TA 1537, TA 98 and TA 100, S. typhimurium TA 1537, S. typhimurium TA 1538, S. typhimurium TA 98, Saccharomyces cerevisiae
- Metabolic activation:
- not specified
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not specified
- Vehicle controls validity:
- not specified
- Untreated negative controls validity:
- not specified
- True negative controls validity:
- not specified
- Positive controls validity:
- not specified
Applicant's summary and conclusion
- Conclusions:
- no Genetic toxicity
- Executive summary:
Predicted endpoint: Gene mutation; No effect specified; E. coli WP2 uvr A, S. typhimurium TA 100, S.
typhimurium TA 1535, S. typhimurium TA 1535, TA 1537, TA 98 and TA 100, S. typhimurium TA 1537,
S. typhimurium TA 1538, S. typhimurium TA 98, Saccharomyces cerevisiae; No duration specified; No
guideline specified
Predicted value: Negative
Unit/scale: Gene mutation I
Data gap filling method: Read-across analysis
Summary: manually editable field
Not provided by the user
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
