Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Eye irritation
Administrative data
- Endpoint:
- eye irritation, other
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: QSAR report
- Title:
- Unnamed
- Year:
- 2 022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR prediction model
- Deviations:
- no
- GLP compliance:
- no
Test material
- Reference substance name:
- tributyl(ethyl)phosphonium 4-methylbenzenesulfonate
- Cas Number:
- 119520-10-4
- Molecular formula:
- C21H39O3PS
- IUPAC Name:
- tributyl(ethyl)phosphonium 4-methylbenzenesulfonate
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Predicted endpoint: chemosis score, conjunctivae score, cornea opacity score, iris score, overall irritation score;
- Score:
- 0.821
- Reversibility:
- not specified
- Remarks on result:
- not determinable because of methodological limitations
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- Prediction of chemosis score, conjunctivae score, cornea opacity score, iris
score, overall irritation score for Tributyl (ethyl) phosphonium ptoluenesulfonate( 1:1) is 0.821 - Executive summary:
Predicted endpoint: chemosis score, conjunctivae score, cornea opacity score, iris score, overall irritation
score; No effect specified; No species specified; No duration specified; No guideline specified
Predicted value: 0.821 (from -1.45 to 3.1)
Unit/scale:
Data gap filling method: Read-across analysis
Summary: manually editable field
Not provided by the user
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
