imidacloprid (ISO); 1-(6-chloropyridin-3-ylmethyl)-N-nitroimidazolidin-2-ylidenamine

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

self-heating substances / mixtures

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is completely molten at 160°C

Reference 2

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

25 Aug - 15 Sep 1993

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

GLP compliance:

yes

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Remarks:

substance melts when approached by the ignition source

No combustion and no propagation of fire was observed - the substance melted.

Interpretation of results:

not classified based on GHS criteria

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

25 Aug - 15 Sep 1993

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

GLP compliance:

yes

Test procedure:

step 1

Remarks on result:

no reaction with water observed

Test procedure:

step 2

Remarks on result:

no reaction with water observed

Test procedure:

step 3

Remarks on result:

no reaction with water observed

Test procedure:

step 4

Remarks on result:

other: minor gas evolution observed in 2 of 3 trials immediately after water addition

Stage 1:

The test substance was added to a dish containing distilled water. No liberation of gas could be observed. Attempts to ignite the gas phase above the dish with the flame of a burner produced negative results.

Stage 2:

The test substance was introduced to a filter paper floating on the surface of the distilled water contained in a dish. No liberation of gas could be observed. Attempts to ignite the gas phase above the filter paper produced negative results.

Stage 3:

A few drops of water were added to a sample of the test substance. No liberation of reaction gasses could be observed. Attempts to ignite the gaseous phase produced negative results.

Stage 4:

Water (approx. 100 mL) was added from a dropping funnel to 12 - 19 g samples of test substance. Three trials were performed. Test sample weights: 15.6 g (trial 1), 12.1 g (trial 2), 19 g (trial 3).

Results (total quantities of liberated gas in cm³, total time 405 min):

Trial 1: 0.6 at t = 0 and at t = 15 min; 0 afterwards

Trial 2: 0.4 at t = 0; 0 afterwards

Trial 3: 0 over the whole period

Minor gas evolution could only be observed in two trials immediately after water addition. The gas production based on one kilogram of test substance and a one hour test period was considerably less than 1 L/kgh in all trials.

The test item does not liberate gases in hazardous amounts in case of contact with water or humid air when tested according to this procedure.

Interpretation of results:

not classified based on GHS criteria

Reference 4

Endpoint:

pyrophoric solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

25 Aug - 15 Sep 1993

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

GLP compliance:

yes

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition on contact with air (not further specified)

Remarks:

no pyrophoric properties at ambient temperature

The test item exhibits no pyrophoric properties at ambient temperature in the sense of Test Procedure EC A.13.

Interpretation of results:

not classified based on GHS criteria

Reference 5

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

GLP compliance:

no

Remarks on result:

not measured/tested

Remarks:

no chemical reaction of the test item in contact with water is expected

According to the chemical structure of Imidacloprid no chemical reaction of the test item in contact with water is expected. The molecule contains no chemical bond which is hydrolysable at room temperature or moderate temperatures above room temperature. Therefore a reaction with water can be excluded. Due to this fact the test item does not form hazardous gases in contact with water.

The test item Imidacloprid (NTN 33893) is not regarded as hazardous in the sense of the consolidated version of Council Directive 67/548/EEC, Annex V, test A.12.

Interpretation of results:

not classified based on GHS criteria

Reference 6

Endpoint:

pyrophoric solids

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

GLP compliance:

no

Test procedure:

ignition time on contact with air

Remarks on result:

not measured/tested

In the chemical structure of Imidacloprid no C-H-bond activated for oxidation by air is present. All other chemical bonds in the given molecule are stable in the presence of air. Due to the chemical structure of the test item pyrophoric properties in contact with air can be excluded.

The test item Imidacloprid (NTN 33893) has no pyrophoric properties in the sense of the consolidated version of Council Directive 67/548/EEC, Annex V, test A.13.

Interpretation of results:

not classified based on GHS criteria

Description of key information

non-flammable on ignition (EU A.10)

non-pyrophoric (EU A.13)

does not liberate hazardous gases on contact with water (EU A.12)

not self-heating

Key value for chemical safety assessment

Flammability:

not classified

Additional information

The substance is non-flammable on ignition as determined in the test according to EU A.10. The solid test item just melted in contact with the ignition source.

The substance is non-pyrophoric as determined in the test according to EU A.13. Non-pyrophoricity can also be deduced from the molecular structure.

The substance does not liberate hazardous gases on contact with water, as determined in an experiment according to EU A.12. This fact is confirmed by an analysis of the molecular structure.

The substance is not self-heating. It is completely molten at the temperature 160 °C.

Justification for classification or non-classification

The available data on flammability of the test substance do not meet the criteria for classification according to Regulation (EC) 1272/2008 and are therefore conclusive but not sufficient for classification: No propagation of burning in a test according to EU Method A.10 was observed - the test item just melted. Based on the results of the tests EU A.13 and EU A.12 and the chemical structure, pyrophoricity and flammability on contact with water, respectively, are not expected. Based on the melting point (< 160 °C) the substance is not self-heating.