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EC number: 221-244-6 | CAS number: 3040-44-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The substance is acutely toxic to aquatic organisms.
Additional information
Short-term toxicity to fish: With high probability acutely not harmful to fish.
Key study: BASF AG (1988, report no. 10F0587/875275). DIN 38412-15, Leuciscus idus:
- 96-h LC50 = 68 mg/L (nom.), without pH-adjustment
- 96-h LC50 > 100 mg/L (nom.), with pH-adjustment
The observed mortality is most likely due to the pH shift in the test solutions caused by the substance, but not due to an inherent toxic effect of the substance.
Short term toxicity to aquatic invertebrates: Acutely harmful to aquatic invertebrates.
Key study: 48-h EC50 = 78.5 mg/L (estimated, QSAR Toolbox v4.4, BASF SE, 2020)
Long-term toxicity to aquatic invertebrates: Based on GHS, no chronic toxicity to aquatic invertebrates is anticipated
Key study: BASF SE (2020, report no. 51E0154/18E038) EC10 (21 d): 4.33 mg/L (nom., analytically verified; Daphnia magna, OECD 211, semi-static)
Toxicity to aquatic algae and cyanobacteria: Acutely toxic to aquatic algae.
Key study: BASF SE (2019, report no. 60E0154/18059): OECD 201, Pseudokirchneriella subcapitata:
72-h ErC50 = 1.56 mg/L (nom., analytically verified)
72-h ErC10 = 0.29 mg/L (nom., analytically verified)
Toxicity to aquatic microorganisms: The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
Key study: hydroxyethylpiperidine (CAS 3040 -44 -6): short-term respiration inhibition study according to OECD 209, municipal activated sludge (GLP; BASF, 2018, 08G0154/18G236):
180 -min EC10 = 73 mg/L (nom.), EC20/EC50 > 1000 mg/L (nom.)
Supp. study: hydroxyethylpiperidine (CAS 3040 -44 -6): short-term respiration inhibition study according to ISO 8192, industrial activated sludge (non-GLP; BASF AG (10 Oct 1985): 30-min EC20 > 100 mg/L (nom.)
Conclusion: 2-Piperidinoethanol (CAS 3040-44-6) is considered to be acutely toxic to aquatic organisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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