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Diss Factsheets
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EC number: 445-090-6 | CAS number: 5614-37-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 October 2001 - 05 December 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to Japanese and OECD test guidelines, and in compliance with GLP, so the data is considered reliable without restriction.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: "Method for Testing the Biodegradability of Chemical Substances by Microorganisms" in "Testing Methods for New Chemical Substances" (July 13, 1974, No. 5, Planning and Coordination Bureau, Environment Agency; No.615 MHW, and No.392, MITI, Japan).
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- - Analytical purity: 99.6%
- Lot/batch No.: 01529 - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Sludge was sampled from 10 locations (a mixture of sewage treatment plants, rivers, lakes and bays) in Japan in September 2001. For city sewage, return sludges from sewage plants were collected; for rivers, lakes and sea locations (bays), surface water and surface soil which was in contact with the atmosphere were collected.
Preparation ofactivated sludge:
Activated sludge was prepared as follows to maintain its uniformity.
The filtrate (5 L) of the supernatant of the activated sludge (The activated sludge cultivated the mixed filtrate (10 L) of the supernatant of sludge collected at the ten locations) cultivated about for 3 months was mixed with the mixed filtrate (5 L) of the supernatant of a sludge collected newly at each location. The mixed filtrate (10 L) was aerated (Prefiltered open air was used.) after the pH value of the mixture was adjusted to 7.0±1.0. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- Residual test material concentration determined by GC at the end of the contact period.
- Details on study design:
- TEST CONDITIONS
- Test temperature: 25±1°C
- pH: 7.0
- pH adjusted: yes
- Suspended solids concentration: 30 mg/L
- Continuous darkness: no
- Other:
TEST SYSTEM
- Number of culture flasks/concentration: 3
- Details of trap for CO2 and volatile organics if used: Soda lime
SAMPLING
- Sampling frequency: Automatically recorded using a data sampler
CONTROL AND BLANK SYSTEM
- Inoculum blank: Yes - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 2
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance): 1 % degradation after 7 d 2 % degradation after 14 d 2 % degradation after 21 d 2 % degradation after 28 d
- Results with reference substance:
- Points of degradation plot (reference substance):
77 % degradation after 7 d
106 % degradation after 14 d
112 % degradation after 21 d
113 % degradation after 28 d - Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
Reference
Description of key information
OECD Guideline 301C, Modified MITI test: not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
A ready biodegradability screening test was conducted (Kurume Laboratory, 2001) to assess the potential for the substance to be degradaed by microorganisms over a 28 -day period. The study was performed according to OECD test guideline 301C (the modified MITI test) and Japanese test guidelines, and in compliance with GLP.
The average percentage biodegradation measured by biochemical oxygen demand (BOD) over the 28 -day exposure period was 2%, and so the substance was concluded not to be readily biodegradable under the test conditions.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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