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Diss Factsheets
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EC number: 916-461-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May from 07 to 12, 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- adopted July 27, 1995
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- Test Item was used in its initial form.
- Melting / freezing pt.:
- -28.8 °C
- Decomposition:
- no
- Conclusions:
- The melting/freezing point of the test item was determined to be -28.8 °C.
- Executive summary:
The thermal behaviour of the substance was investigated using the Differential Scanning Calorimetry method, according to the OECD guideline 102.
In order to check the approximate freezing temperature, 1 ml of the test item was transferred into 2 ml cryovials. Four replicate tubes were placed in the freezer (-15 to -30 °C). After at least 24 hours storage period two replicate tubes were removed and the physical state of the test item was examined. The test item was frozen in the tubes, therefore the main test was conducted.
A small amount of test item was weighed into a one-way 40 µl aluminum crucible and sealed with pierced aluminum lid using a capsule presser. Thus prepared capsule was inserted into the furnace of the DSC device and cooled from room temperature to -40 °C with 0.5 °C/min cooling rate and then heated again to room temperature with 0.5 °C/min heating rate. The measurement was performed under nitrogen atmosphere and the experiment was performed in duplicate.
Before the test the appearance of the test item was yellow liquid. After the experiments the test item became black, porous and its volume increased in the crucible. Before the test the appearance of the test item was yellow liquid. After the experiments the test item became black, porous and its volume increased in the crucible.
Conclusion
The melting/freezing point of the test item was determined to be -28.8 °C.
Reference
MAIN TEST
During the cooling down phase of the DSC runs one exothermic peak was observed at ca. 0 °C, attributed to the freezing temperature of the water content of test item. During the cooling/heating phases at ca. -29 °C glass transition was observed which was assumed the freezing/melting point of test item. Midpoint ISO temperature was used for the calculation of the mean freezing/melting point.
Experiment Phase | Sample weight [mg] | Onset of effect [°C] | Midpoint ISO [°C] | Mean Midpoint ISO [°C] | |
Exp. 1 | Cooling down | 3.39 | -26.53 | -27.82 | -28.90 |
Heating up | -30.18 | -29.97 | |||
Exp. 2 | Cooling down | 6.86 | -26.49 | -27.51 | -28.72 |
Heating up | -30.12 | -29.92 |
Before the test the appearance of the test item was yellow liquid. After the experiments the test item became black, porous and its volume increased in the crucible.
PRELIMINARY TEST
Observations during the freezing point test
Temperature (°C) | Storage period (hours) | State of the samples | |
Replicate 1 | Replicate 2 | ||
-30 | 24 | solid | solid |
-30 | 48 | solid | solid |
Description of key information
The melting/freezing point of the test item was determined to be -28.8 °C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -28.8 °C
Additional information
OECD 102 - Differential Scanning Calorimetry method
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