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EC number: 466-380-9 | CAS number: 52350-17-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 Feb 2017 - 18 Feb 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Department of Health, London, UK
- Type of method:
- effusion method: vapour pressure balance
Test material
- Test material form:
- solid: nanoform, no surface treatment
Constituent 1
Results and discussion
Vapour pressure
- Temp.:
- 25 °C
- Vapour pressure:
- ca. 0.001 Pa
- Remarks on result:
- other: Result is average of extrapolated measured values from 5 runs.
Any other information on results incl. tables
Results
Recorded temperatures, mass differences and the resulting calculated
values of vapour pressure are shown in the following tables:
Table 1 – Run 1 results
Temperature [°C] |
Temperature [K] |
Reciprocal temperature [K^-1] |
Mass difference [µg] |
Mass difference [kg] |
Vapour pressure [Pa] |
Log Vp |
45 |
318.15 |
0.003143171 |
4.14 |
4.140E-09 |
0.005747381 |
-2.240530038 |
46 |
319.15 |
0.003133323 |
4.37 |
4.370E-09 |
0.006066680 |
-2.217048942 |
47 |
320.15 |
0.003123536 |
4.33 |
4.330E-09 |
0.006011149 |
-2.221042482 |
48 |
321.15 |
0.003113810 |
5.86 |
5.860E-09 |
0.008135181 |
-2.089632763 |
49 |
322.15 |
0.003104144 |
5.00 |
5.000E-09 |
0.006941281 |
-2.158560374 |
50 |
323.15 |
0.003094538 |
5.98 |
5.980E-09 |
0.008301772 |
-2.080829195 |
51 |
324.15 |
0.003084992 |
4.08 |
4.080E-09 |
0.005664085 |
-2.246870216 |
52 |
325.15 |
0.003075504 |
7.43 |
7.430E-09 |
0.010314744 |
-1.986541565 |
53 |
326.15 |
0.003066074 |
7.27 |
7.270E-09 |
0.010092623 |
-1.995995968 |
54 |
327.15 |
0.003056702 |
8.85 |
8.850E-09 |
0.012286067 |
-1.910587108 |
55 |
328.15 |
0.003047387 |
9.97 |
9.970E-09 |
0.013840914 |
-1.858835220 |
A plot of Log10(vapor pressure (Pa)) versus reciprocal
temperature (1/T(K)) for Run 1 gives the following statistical data
using an unweighted least squares treatment.
Slope: -3.72E03
Standard error in slope: 749
Intercept: 9.42
Standard error in intercept: 2.32
The results obtained indicate the following vapour pressure
relationship: log (Vp(Pa)) = -3.72E03 / temp (K) + 9.42
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -3.06.
Table 2 – Run 2 results
Temperature [°C] |
Temperature [K] |
Reciprocal temperature [K^-1] |
Mass difference [µg] |
Mass difference [kg] |
Vapour pressure [Pa] |
Log Vp |
45 |
318.15 |
0.003143171 |
2.27 |
2.270E-09 |
0.003151342 |
-2.501504522 |
46 |
319.15 |
0.003133323 |
4.21 |
4.210E-09 |
0.005844559 |
-2.233248283 |
47 |
320.15 |
0.003123536 |
4.08 |
4.080E-09 |
0.005664085 |
-2.246870216 |
48 |
321.15 |
0.003113810 |
4.25 |
4.250E-09 |
0.005900089 |
-2.229141449 |
49 |
322.15 |
0.003104144 |
4.87 |
4.870E-09 |
0.006760808 |
-2.170001418 |
50 |
323.15 |
0.003094538 |
5.42 |
5.420E-09 |
0.007524349 |
-2.123531092 |
51 |
324.15 |
0.003084992 |
5.88 |
5.880E-09 |
0.008162946 |
-2.088153053 |
52 |
325.15 |
0.003075504 |
6.31 |
6.310E-09 |
0.008759897 |
-2.057501019 |
53 |
326.15 |
0.003066074 |
7.44 |
7.440E-09 |
0.010328626 |
-1.985957443 |
54 |
327.15 |
0.003056702 |
8.11 |
8.110E-09 |
0.011258758 |
-1.948509525 |
55 |
328.15 |
0.003047387 |
8.39 |
8.390E-09 |
0.011647470 |
-1.933768418 |
A plot of Log10(vapor pressure (Pa)) versus reciprocal
temperature (1/T(K)) for Run 2 gives the following statistical data
using an unweighted least squares treatment.
Slope: -4.93E03
Standard error in slope: 548
Intercept: 13.1
Standard error in intercept: 1.70
The results obtained indicate the following vapour pressure
relationship: log (Vp(Pa)) = -4.93E03 / temp (K) + 13.1
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -3.42.
Table 3 – Run 3 results
Temperature [°C] |
Temperature [K] |
Reciprocal temperature [K^-1] |
Mass difference [µg] |
Mass difference [kg] |
Vapour pressure [Pa] |
Log Vp |
45 |
318.15 |
0.003143171 |
3.51 |
3.510E-09 |
0.004872779 |
-2.312223262 |
46 |
319.15 |
0.003133323 |
3.97 |
3.970E-09 |
0.005511377 |
-2.258739872 |
47 |
320.15 |
0.003123536 |
4.80 |
4.800E-09 |
0.006663630 |
-2.176289141 |
48 |
321.15 |
0.003113810 |
4.09 |
4.090E-09 |
0.005677968 |
-2.245807071 |
49 |
322.15 |
0.003104144 |
4.56 |
4.560E-09 |
0.006330448 |
-2.198565536 |
50 |
323.15 |
0.003094538 |
5.50 |
5.500E-09 |
0.007635409 |
-2.117167689 |
51 |
324.15 |
0.003084992 |
5.75 |
5.750E-09 |
0.007982473 |
-2.097862534 |
52 |
325.15 |
0.003075504 |
6.25 |
6.250E-09 |
0.008676601 |
-2.061650361 |
53 |
326.15 |
0.003066074 |
6.79 |
6.790E-09 |
0.009426260 |
-2.025660604 |
54 |
327.15 |
0.003056702 |
7.58 |
7.580E-09 |
0.010522982 |
-1.977861173 |
55 |
328.15 |
0.003047387 |
8.78 |
8.780E-09 |
0.012188889 |
-1.914035863 |
A plot of Log10(vapor pressure (Pa)) versus reciprocal
temperature (1/T(K)) for Run 3 gives the following statistical data
using an unweighted least squares treatment.
Slope: -3.83E03
Standard error in slope: 308
Intercept: 9.72
Standard error in intercept: 0.953
The results obtained indicate the following vapour pressure
relationship: log (Vp(Pa)) = -3.83E03 / temp (K) + 9.72
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -3.12.
Table 4 – Run 4 results
Temperature [°C] |
Temperature [K] |
Reciprocal temperature [K^-1] |
Mass difference [µg] |
Mass difference [kg] |
Vapour pressure [Pa] |
Log Vp |
45 |
318.15 |
0.003143171 |
2.47 |
2.470E-09 |
0.003428993 |
-2.464833425 |
46 |
319.15 |
0.003133323 |
2.81 |
2.810E-09 |
0.003901000 |
-2.408824059 |
47 |
320.15 |
0.003123536 |
4.03 |
4.030E-09 |
0.005594672 |
-2.252225333 |
48 |
321.15 |
0.003113810 |
4.29 |
4.290E-09 |
0.005955619 |
-2.225073087 |
49 |
322.15 |
0.003104144 |
4.75 |
4.750E-09 |
0.006594217 |
-2.180836769 |
50 |
323.15 |
0.003094538 |
4.87 |
4.870E-09 |
0.006760808 |
-2.170001418 |
51 |
324.15 |
0.003084992 |
4.50 |
4.500E-09 |
0.006247153 |
-2.204317865 |
52 |
325.15 |
0.003075504 |
5.85 |
5.850E-09 |
0.008121299 |
-2.090374513 |
53 |
326.15 |
0.003066074 |
5.93 |
5.930E-09 |
0.008232359 |
-2.084475685 |
54 |
327.15 |
0.003056702 |
7.48 |
7.480E-09 |
0.010384156 |
-1.983628781 |
55 |
328.15 |
0.003047387 |
7.83 |
7.830E-09 |
0.010870046 |
-1.963768617 |
A plot of Log10(vapor pressure (Pa)) versus reciprocal
temperature (1/T(K)) for Run 4 gives the following statistical data
using an unweighted least squares treatment.
Slope: -4.71E03
Standard error in slope: 470
Intercept: 12.4
Standard error in intercept: 1.46
The results obtained indicate the following vapour pressure
relationship: log (Vp(Pa)) = -3.8E03 / temp (K) + 12.4
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -3.40.
Table 5 – Run 5 results
Temperature [°C] |
Temperature [K] |
Reciprocal temperature [K^-1] |
Mass difference [µg] |
Mass difference [kg] |
Vapour pressure [Pa] |
Log Vp |
45 |
318.15 |
0.003143171 |
3.90 |
3.900E-09 |
0.005414199 |
-2.266465772 |
46 |
319.15 |
0.003133323 |
3.51 |
3.510E-09 |
0.004872779 |
-2.312223262 |
47 |
320.15 |
0.003123536 |
3.16 |
3.160E-09 |
0.004386890 |
-2.357843296 |
48 |
321.15 |
0.003113810 |
4.46 |
4.460E-09 |
0.006191623 |
-2.208195520 |
49 |
322.15 |
0.003104144 |
4.38 |
4.380E-09 |
0.006080562 |
-2.216056268 |
50 |
323.15 |
0.003094538 |
4.31 |
4.310E-09 |
0.005983384 |
-2.223053109 |
51 |
324.15 |
0.003084992 |
4.75 |
4.750E-09 |
0.006594217 |
-2.180836769 |
52 |
325.15 |
0.003075504 |
5.34 |
5.340E-09 |
0.007413288 |
-2.129989122 |
53 |
326.15 |
0.003066074 |
5.86 |
5.860E-09 |
0.008135181 |
-2.089632763 |
54 |
327.15 |
0.003056702 |
6.25 |
6.250E-09 |
0.008676601 |
-2.061650361 |
55 |
328.15 |
0.003047387 |
7.16 |
7.160E-09 |
0.009939914 |
-2.002617356 |
A plot of Log10(vapor pressure (Pa)) versus reciprocal
temperature (1/T(K)) for Run 5 gives the following statistical data
using an unweighted least squares treatment.
Slope: -3.14E03
Standard error in slope: 427
Intercept: 7.54
Standard error in intercept: 1.32
The results obtained indicate the following vapour pressure
relationship: log (Vp(Pa)) = -3.14E03 / temp (K) + 7.54
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -3.00.
The vapour pressure values at 25 °C extrapolated from each graph are shown below.
Table 6 – Summary of vapour pressure data
Run |
Log10 [Vp [25 °C]] |
1 |
-3.06 |
2 |
-3.42 |
3 |
-3.12 |
4 |
-3.40 |
5 |
-3.00 |
Mean |
-3.20 |
Vapour pressure |
6.32E-04 Pa |
Discussion
The test item did not change in appearance under the conditions used in
the determination.
A total of 5 runs were completed for the main sequence. Equilibrium with regard to vapor pressure was assessed to have been reached over the 5 runs. Thus all 5 runs have been used to calculate the definitive vapor pressure value for the test item.
The results may represent rounded values obtained by calculations based on the exact raw data.
Conclusion
The vapor pressure of the test item has been determined to be 6.3 x 10-4
Pa at 25 ºC.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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