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EC number: 283-626-9 | CAS number: 84696-07-1 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Cupressus sempervirens, Pinaceae.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
An acute aquatic toxicity study was performed on Daphnia magna in accordance with GLP and OECD Guideline No 202 and WAF conditions.
Under the test conditions, the 48h-EC50 of CYPRESS OIL on Daphnia magna was 3.0 mg/L, based on mean measured concentrations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3 mg/L
Additional information
An acute aquatic toxicity study was performed on Daphnia magna in accordance with GLP and OECD Guideline No 202 and WAF conditions. Twenty daphnids (four replicates, five daphnids per replicate) were exposed to an aqueous solution of Cypress oil at the required nominal test concentrations of 1.5, 1.9, 2.4, 3.1, 3.9 and 5.0 mg test item.L-1. Immobilisation of daphnids was determined in a semi-static 48-h test by visual observation after 24 and 48 h.
The concentrations of the test item were measured at the start (t = 0 h), at t = 24 h (new and old solutions) and at the end of the test (t = 48 h). Sufficient analytical evidence is provided that every effort was made to maintain the WAFs concentrations. However, initial measured concentrations were lower compared to their nominal values (loading rates). The analytical results showed that WAFs were enough stable over the study period (overall within or close to the ± 20% of the initial concentration). However, a WAF is by definition for complex mixtures for which individual concentration of each constituent differs dur to own properties. For this reason it was consider acceptable to base the results on nominal loading values. At 24h, immobilisaiton was at 0% 1.5, 1.9, 2.4, 3.1 mg test item.L-1 (loading), 5% at 3.9mg/L (loading) and 90% at 5.0mg/L (loading).
At 48h, immobilization was 0% at 1.5, 1.9, 2.4 mg test item.L-1 (loading), 75% at 3.1 mg test item.L-1 and 100% at 3.9 and 5.0 mg test item.L-1 (loading).
Therefore, the 48h-EC50of Cypress oil for Daphnia magna was estimated to be 3.0 mg/L.
Based on the results of this study, Cypress oil would not be classified as acute 1 to aquatic organisms in accordance with the classification of the CLP.
This toxicity study is acceptable and can be used for that endpoint.
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