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Diss Factsheets
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EC number: 607-233-2 | CAS number: 2343-89-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13/4/14 to 11/5/15
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: US EPA Fate, Transport and Transformation Test Guidelines OCSPP 835.3110 (Paragraph (q))
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Secondary effluent of a domestic sewage treatment plant (Loughborough)
- Storage conditions: Aerated at 20 ± 1oC
- Pre-treatment: Separation of coarse particles by filtration
- Concentration of sludge: 1% v/v - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- Incubation temperature: 23 ± 1oC
- Preliminary study:
- No data
- Test performance:
- No data
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 21
- Sampling time:
- 7 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 29
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 33
- Sampling time:
- 21 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 35
- Sampling time:
- 28 d
- Results with reference substance:
- % degradation of reference substance (aniline)
14% degradtion after 7-d
70% degradation after 14-d
89% degradation after 21-d
99% degradatino after 28-d - Interpretation of results:
- other: Not readily biodegradable
- Conclusions:
- The substance was not readily biodegradable under the employed test conditions
- Executive summary:
A study was performed to assess the ready biodegradability of test substance according to Directive 92/69/EEC, method C.4 -D (Determination of 'ready' biodegradability - Manometric respiration test) and the equivalent OECD guideline 301F, in compliance with GLP.
The test substance in a mineral medium was inoculated with secondary domestic effluent and incubated for 28 d under aerobic conditions. During this period the biodegradation was followed by percentage BOD (CO2evolution) based on the initial nominal concentration present.
The test substance showed 21, 29, 33 and 35 % degradation after 7, 14, 21, 28 d. Therefore, the test substance is classified as not readily biodegradable. The reference substance showed 70 % degradation after 14 d. The toxicity control showed 61% degradation after 14 d.
Under the employed test conditions, the test substance is considered not to be readily biodegradable. In addition, the test substance was not considered to have an inhibitory effect on the sewage treatment process microorganisms at the test concentration of 100 mg/l.
Reference
Day |
% Degradation |
||
Test substance |
Reference substance |
Toxicity control |
|
7 |
21 |
14 |
9 |
14 |
29 |
70 |
61 |
21 |
33 |
89 |
70 |
28 |
35 |
99 |
72 |
Description of key information
A reliable study (Klimisch 1) assessed biodegradability using a standard method equivalent to OECD guideline 301F, in compliance with GLP.
After 28 days a maximum of 35% degradation was observed, therefore, the test substance should be considered as not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable, not fulfilling specific criteria
Additional information
The test substance in a mineral medium was inoculated with secondary domestic effluent and incubated for 28 d under aerobic conditions. Biodegradation was determined by percentage BOD (CO2 evolution) based on the initial nominal concentration present. The test substance showed 21, 29, 33 and 35 % degradation after 7, 14, 21, 28 days, respectively. Therefore, the test substance should be considered as not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.