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EC number: 231-977-3 | CAS number: 7783-06-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Exposure to hydrogen sulfide and respiratory function
- Author:
- Jappinen P, Vilkka V, Marttila O, et al.
- Year:
- 1 990
- Bibliographic source:
- Br. J. Ind. Med. 47: 824-828
- Reference Type:
- secondary source
- Title:
- Hydrogen sulfide - Interim acute exposure guideline levels (AEGLs) for NAS/COT suncommittee for AEGLs
- Author:
- Anonymous
- Year:
- 2 002
- Bibliographic source:
- http://www.epa.gov/oppt/aegl/pubs/hydrogen_sulfide_interim_nov_2002.pdf
Materials and methods
Test material
- Reference substance name:
- Hydrogen sulphide
- EC Number:
- 231-977-3
- EC Name:
- Hydrogen sulphide
- Cas Number:
- 7783-06-4
- Molecular formula:
- H2S
- IUPAC Name:
- hydrogen sulfide
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
A group of 10 asthmatics (3 men age 33-50 and 7 women age 31-61) was exposed to 2 ppm hydrogen sulfide for 30 minutes. The subjects had been diagnosed bronchial asthmatics for 1 to 13 years and were under medical supervision. Severe asthmatics were excluded from the protocol. Two of the volunteers were exposed simultaneously in a 10m3 sealed tile walled exposure chamber with an oxygen flow of 2 L/min. Hydrogen sulfide concentration was monitored continuously with a sulfur dioxide analyzer connected to a converter that transformed hydrogen sulfide into sulfur dioxide at 840°C. The hydrogen sulfide was supplied to the chamber from laminated plastic bags through plastic tubing. All asthmatic subjects complained of an unpleasant odor and nasal and pharyngeal dryness at initiation of exposure. Three of the ten complained of headache after exposure. There were no significant effects on FVC, FEV1, or FEF values after exposure to hydrogen sulfide. Airway resistance (Raw) value was slightly decreased in two and increased in eight subjects. The range of Raw differences was -5.95% to +137.78 % with an average increase of 26.3%; no accompanying clinical symptoms were observed. The range of specific airway conductance (SGaw) differences was -57.7% to +30%, with an average decrease of 8.4%. These effects were not statistically significant; however, in two subjects, changes were greater than 30% in both Raw and Sgaw.
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