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EC number: 219-280-2 | CAS number: 2402-58-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (3h) > 1000 mg/L (nominal) for respiration inhibition of activated sludge (OECD 209), read across
Key value for chemical safety assessment
- EC50 for microorganisms:
- 10 g/L
Additional information
One study is available with Didodecyl fumarate (CAS 2402-58-6), performed according to a German national guideline DIN 38412, part 27 (Kirch, 1995). In this study the inhibition of oxygen consumption for a 10000 mg/L filtered test item solution was measured after 30 min exposure time with Pseudomonas putida. As no inhibition was observed, the EL50 (30 min) is > 10000 mg/L. The test is reliable, but not appropriate enough for current regulatory demands and is therefore used as supporting information. Therefore, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 Grouping of substances, a read-across to the structurally related category member Ditetradecyl fumarate (CAS 10341-03-4) was conducted. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance within this category was used.
The study with Ditetradecyl fumarate (CAS 10341-03-4) was performed according to OECD 209 and GLP using domestic activated sludge as inoculum (Hammer, 2013). Concentrations of 62.5, 125, 250, 500 and 1000 mg/L (nominal) were tested. The test substance was added in the required amounts according to the test concentrations directly to the test vessels. No respiration inhibition was observed up to the highest test substance concentration. The EC10 and EC50 are therefore > 1000 mg/L.
Due to the structural and property similarities with the tested category member Ditetradecyl fumarate (CAS 10341-03-4) this result is applicable to read across to Didodecyl fumarate (CAS 2402-58-6).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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