Registration Dossier
Registration Dossier
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EC number: 253-168-4 | CAS number: 36727-29-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound 3,5,5-trimethylhexanoyl chloride: Acutely harmful to
aquatic invertebrates.
Hydrolysis product 3,5,5-trimethylhexanoic acid: Acutely harmful to
aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The short term toxicity to aquatic invertebrates of the parent compound 3,5,5-trimethylhexanoyl chloride was tested on Daphnia magna according to Directive 79/831/EEC, Annex V, Part C. The 48h EC50 was 26.9 mg/L (BASF AG, 1989). The test item concentrations were not analytically verified. Since 3,5,5-trimethylhexanoyl chloride rapidly decomposes in water and forms hydrochloric acid (CAS 7647-01-0) and 3,5,5-trimethylhexanoic acid (CAS 3302-10-1), the reported effect may at least be partially related to degradation products.
The short term toxicity to aquatic invertebrates of the hydrolysis product 3,5,5-trimethylhexanoic acid (CAS 3302-10-1) was tested on Daphnia magna in a GLP guideline study according to OECD 202 (Harlan, 2010, C84121). The 48h EC50 was 68 mg/L (test item concentrations analytically verified).
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