Registration Dossier
Registration Dossier
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EC number: 247-728-7 | CAS number: 26479-35-6
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Bioaccumulation testing in aquatic/benthic species is not required for substances with a low potential for bioaccumulation. Potassium allophonate has an experimentally determined log Pow ≤ -1.08, and given a lack of any lipophilic moieties in the chemical structure, the entire structure of potassium allophonate is hydrophilic and thus it has a low potential to cross biological membranes. Therefore, potassium allophonate has a low potential for bioaccumulation and testing for this endpoint is waived in accordance with Column 2 of Annex IX of Regulation (EC) No. 1907/2006.
Key value for chemical safety assessment
Additional information
According to Column 2 of Annex IX of Regulation (EC) No. 1907/2006, bioaccumulation in aquatic/benthic species testing is not required for substances with a low potential for bioaccumulation (e.g., log octanol-water partition coefficient [log Pow] <3) and/or a low potential to cross biological membranes. Potassium allophonate meets both of these criteria. The experimentally-determined log Pow of potassium allophonate is ≤ -1.08 (ABC Laboratories, 2012a), and given a lack of any lipophilic moieties in the chemical structure, the entire structure of potassium allophonate is hydrophilic and thus it has a low potential to cross biological membranes.
References:
ABC Laboratories, Inc. 2012a. Potassium Allophonate: Determination of n-Octanol/Water Partition Coefficient by High Performance Liquid Chromatography (HPLC). Testing laboratory: ABC Laboratories, Inc. 7200 E. ABC Lane, Columbia, MO 65202. Owner Company: Kerr Fire Fighting Chemicals, Ashcroft Rd., Knowsley Industrial Park, Kirby, Liverpool L33 7TS, England. Company study no.: 68014. Report date: 2012-05-14.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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