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EC number: 244-169-0 | CAS number: 21049-70-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The test substance is soluble in water and dissociates.
Since no studies on the aquatic toxicity of 2-(methylamino)ethanol, compound with sulphur dioxide are available, study reports about the toxic effects of 2-(methylamino)ethanol and substances of the sulphite category have been consulted alternatively.
The acute toxicity of 2-(methylamino)ethanol (CAS 109-83-1) to microorganisms was examined in a guideline study according to OECD 209 [BASF AG, 1993] using domestic activated sludge as inoculum. At test termination after 30 minutes, an EC20 > 1000 mg/L was determined.
A respiration inhibition test was conducted with the read-across substance sodium sulfite Na2SO3(CAS 7757-83-7) according to OECD guideline 209 [ECT 2010]. No respiratory effects were noticed at 1000 mg Na2SO3/L. Thus, the NOEC expressed as SO32-was equal to (or higher than) 634.4 mg/L.
Supporting growth inhibition tests with the bacteria Pseudomonas putida were conducted with three different sulphite compounds: potassium sulphite K2SO3(CAS 10117-38-1), disodium disulphite Na2S2O5(CAS 7681-57-4) and dipotassium disulphite K2S2O5(CAS 16731-55-8) [BASF AG, 1988].At test termination after 17 hours, results show EC10 values ranging from 23.1 - 77.4 mg SO32-/L. As the respiration inhibition test with activated sludge is a more relevant test design for evaluating effects of a substance on microorganisms, and taking into account that the ECT-study was conducted as GLP-compliant OECD guideline study, these data (i.e. NOEC >= 634.4 mg/L) are put forward for the effects assessment of sulphite/disulphite compounds towards microorganisms.
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