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EC number: 406-040-9 | CAS number: 125643-61-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects occur at the range of solubility.
Key value for chemical safety assessment
Additional information
Assessment of the parent compound Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters (CAS: 125643 -61 -0)
Two 48 hour static tests without vehicle (OECD 202): Two valid acute toxicity tests using Daphnia magna are available for Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters. Both tests were performed according to OECD guideline 202, representing limit tests, where water accomodated fractions (WAF) of 100 mg/L loading rate and a control were tested in parallel. According to RCC (2002), the analytically determined test item concentration in the analyzed test medium samples of the undiluted filtrate taken at the start and end of the test was below the limit of quantification of the analytical method of 0.023 mg/L. The biological results were therefore based on the loading rate of 100 mg/L. In the control and in the undiluted filtrate with the loading rate of 100 mg/L, no immobilized test organisms were determined during the test period of 48 hours. This result is supported by a non GLP screening test where no immobilized test organisms were determined at 100 mg/L loading rate (RCC 1998). In the control 10% of daphnids were immobilized. Therefore, Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters are unlikely to cause acute toxic effects to aquatic invertebrates.
Supporting assessment of the impurity Metilox (CAS 6386-38-5)
In a 24-h acute toxicity to Daphnia magna under static conditions. The 24 -h EC50 was > 100 mg/L, the 24 -h EC0 based on immobilization was 5.8 mg/L.
Supporting assessment of the major degradation product Metilox acid (CAS: 20170-32-5)
In a short-term toxicity test on Daphnia magna, the EC50 (48 h) was found to be greater than 121 mg/L (measured).
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