Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

2-Propanol, 1,1’-[[3-[(3-Aminopropyl)Amino]Propyl]Imino]Bis-, N-Tallow Alkyl Derivatives

is not readily biodegradable according to OECD guideline criteria and are expected to strongly sorb on soil and sediment particles based on modeled Koc.

Determination of the hydrolysis rate for 2-Propanol, 1,1’-[[3-[(3-Aminopropyl)Amino]Propyl]Imino]Bis-, N-Tallow Alkyl Derivatives

is considered not to be technically possible due to its low water solubility and the fact that it is a complex substance comprising numerous components (UVCB). A waiver is therefore proposed for this test.

No actual data are available for determining fish bioaccumulation potential for 2-Propanol, 1,1’-[[3-[(3-Aminopropyl)Amino]Propyl]Imino]Bis-, N-Tallow Alkyl Derivatives.

Nevertheless modeling approach using data coming from a surrogate substance (

Amines, N-tallow alkyltrimethylenedi-, propoxylated)

tends to indicate that the substance is not bioaccumulable in organisms with an estimated BCF < 2,000.

In addition, relevant available data on 2-Propanol, 1,1’-[[3-[(3-Aminopropyl)Amino]Propyl]Imino]Bis-, N-Tallow Alkyl Derivatives.

was analyzed to assess its potential toxicokinetic behaviour in mammals (see section 7.1.1. of the iuclid 5). The absorbance is expected to be low, while the metabolisation of amines common reactions of xenobiotic metabolism. Therefore a tendency for bioaccumulation is not expected. Metabolites will be excreted both via urine and bile (feces) depending on the size and charge of the molecules.

Thus, these data show that 2-Propanol, 1,1’-[[3-[(3-Aminopropyl)Amino]Propyl]Imino]Bis-, N-Tallow Alkyl Derivatives.

is not expected to bioaccumulate.