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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 August to 21 Novemver 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted to current test guidelines in accordance with GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate
EC Number:
411-700-4
EC Name:
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate
Cas Number:
140921-24-0
Molecular formula:
C32H62N4O6
IUPAC Name:
2-[3-(heptan-3-yl)-1,2-oxazolidin-2-yl]ethyl N-{6-[({2-[3-(heptan-3-yl)-1,2-oxazolidin-2-yl]ethoxy}carbonyl)amino]hexyl}carbamate

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
8

Any other information on results incl. tables

A 4048 mg/l stock solution of the test substance was prepared in acetonitrile. The stock solution was injected into the HPLC system as such, to avoid degradation of the test substance in aqueous matrix. The test substance blank solution was acetonitrile. The reference substance- and test substance solutions were injected in duplicate. Blank solutions were analysed by single injection.

Applicant's summary and conclusion

Conclusions:
The log Pow is claculated to be 8
Executive summary:

The partition coefficient was calculated according to the OECD Guideline 117 (n-octanol / water), HPLC Method. A 4048 mg/l stock solution of the test substance was prepared in acetonitrile. The stock solution was injected into the HPLC system as such, to avoid degradation of the test substance in aqueous matrix. The test substance blank solution was acetonitrile. The reference substance- and test substance solutions were injected in duplicate. Blank solutions were analysed by single injection. The logPow was calculated to be 8.