Registration Dossier
Registration Dossier
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EC number: 204-409-7 | CAS number: 120-57-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 11th November 1997 to 11th December 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- GLP study in compliance with international recognized guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 1.2
- Temp.:
- 35 °C
- Remarks on result:
- other: data on pH not available
- Conclusions:
- The partition coefficient n-octanol/water of heliotropin (piperonal) is log Pow: 1.2 at 35°C
Reference
The determination was performed at 35 °C (temperature of the column), but the value obtained above can be considered to represent the value at an unspecified, probably ambient temperature since no mention is made in the guidelines of the temperature at which the tabulated reference substances log Pow values were determined. Partition coefficients of the test and reference substances are assumed to vary with temperature in the same way.
Description of key information
LogPow (OECD117): 1.2 at 35°C
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.2
- at the temperature of:
- 35 °C
Additional information
The determination of log Pow was performed at 35 °C (temperature of the column) according to OECD 117, but the value reported above can be considered to represent the value at an unspecified, probably ambient temperature since no mention is made in the guidelines of the temperature at which the tabulated reference substances log Pow values were determined. Partition coefficients of the test and reference substances are assumed to vary with temperature in the same way.
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