Registration Dossier
Registration Dossier
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EC number: 201-126-0 | CAS number: 78-59-1
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A geometric mean of the lower and upper chronic endpoints, as determined in early-life-stage tests, was 14 mg/L (based on measured test concentrations).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 14 mg/L
Additional information
Experimental data are available for the assessment of the long-term toxicity of isophorone to fish. In a publication of Cairns and Nebeker (1982) the long-term toxicity of the substance was assessed in a flow-through early life stage toxicity test (US EPA, 1979) with a Pimephales promelas as a test organism. In this test the survival of test organisms was affected by 112 mg isophorone/L but not by56mg/L and lower. Fork Iength was affected by 30 mg/L and higher but not by19 mg/Land lower; weight was affected by19 mg/Land higher but not by 11 mg/L. A geometric mean of the lower and upper chronic endpoints, as determined in early-life-stage tests, was 14 mg/L (basedon measured test concentrations).
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