N-octylpyridin-4-amine

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Experimental starting date: 16 January 2018, Experimental completion date: 11 May 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

N-octylpyridin-4-amine

EC Number:

265-019-0

EC Name:

N-octylpyridin-4-amine

Cas Number:

64690-19-3

Molecular formula:

C13H22N2

IUPAC Name:

N-octylpyridin-4-amine

Results and discussion

Boiling point

Key result

Boiling pt.:

352 °C

Atm. press.:

102 kPa

Any other information on results incl. tables

Results

The thermograms and thermographic data for Determinations 1 to 4 are shown in the following figures and table:

See below for figures.

Table 2

Thermal event	Interpretation	Temperature (°C)
		Det 1	Det 2	Det 3	Det 4
Endotherm	Onset of boiling	283.14	276.75	320.20	320.04
	Extrapolated onset of boiling	351.15	351.46	352.17	351.37

 

Atmospheric pressure:

Determination 1 and 2: 102 kPa

Determination 3 and 4: 101 kPa

After heating to 400 °C, the samples had lost approximately 100% of their original weight for Determinations 1, 2 and 3; while Determination 4 had lost approximately 94%.

Overall boiling point result: 352 ± 1 °C (625 ± 1 K)

 

Discussion

Determinations 1 and 2 showed significantly more volatilization prior to boiling due to the larger hole of the manually pierced lid. Therefore, additional determinations were performed using pre-perforated lids which create a self-generated atmosphere and suppress volatilization of the test item.

Determination 4 may have lost only 94% of its original weight due to the inaccuracies of weighing a small mass, and in reality may have lost approximately 100%.

The endotherm at approximately 65 °C in Determinations 1 and 2 was that of melting point. This was a slightly higher temperature than determined in the Melting point section of this report due to the higher heating rate used for the boiling point determination.

 

Conclusion

The test item was determined to have a boiling point at 352 ± 1 °C (625 ± 1 K) at 100 to 101 kPa.

Applicant's summary and conclusion

Conclusions:

The test item was determined to have a boiling point at 352 ± 1 °C (625 ± 1 K) at 100 to 101 kPa