Aluminum magnesium oxide

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

ISO 13320 (Particle size analysis - Laser diffraction methods)

Version / remarks:

Part 1, 2009

Deviations:

no

Principles of method if other than guideline:

According to REACH Article 13(3) tests on substances shall be conducted in accordance with the test methods laid down in a Commission Regulation or in accordance with other international test methods recognised by the Commission or the Agency as being appropriate. No particle size distribution test method is laid down in regulation (EC) No 440/2008. OECD 110 TG ‘Particle Size Distribution/Fibre Length and Diameter Distributions’ dates from 1981 and describes two methods in detail; both methods have restrictions and are not applicable to the entire size range. ECHA’s Guidance on information requirements and Chemical Safety Assessment-Chapter R.7a stipulates that many methods are available for particle size measurements but none of them is applicable to the entire size range. The guidance mentions Laser scattering/diffraction as a method for particles of all kind and makes reference to ISO 13320:2009.

According to Guidance document EUR 20268 (2002), the laser diffraction technique is applicable to particles of respirable and inhalable size. The MMAD can be calculated when density is known.

GLP compliance:

no

Type of method:

Laser scattering/diffraction

Type of particle tested:

primary particle

Type of distribution:

volumetric distribution

Specific details on test material used for the study:

Material was tested 'as received' and tested as 'dried at 200°C for 16h under vacuum'.

Mass median aerodynamic diameter:

25.61 µm

Remarks on result:

other: MMAD based on the D50 mean value obtained with 1 bar venturi pressure

Key result

Percentile:

D10

Mean:

2.1 µm

Remarks on result:

other: n= 2, based on results obtained with 1 bar venturi pressure

Key result

Percentile:

D50

Mean:

14.7 µm

Remarks on result:

other: n= 2, based on results obtained with 1 bar venturi pressure

Key result

Percentile:

D90

Mean:

116.3 µm

Remarks on result:

other: n= 2, based on results obtained with 1 bar venturi pressure

No.:

#1

Size:

<= 10 µm

Distribution:

31.3 %

Remarks on result:

other: volume of sample

Conclusion of visual evaluation: white substance with small particles and larger particles (lumps) present

PSD graphs (volume % vs particle diameter) and more details on particle size data in relation to dispersion (venturi) pressure are presented as 'attached background material'

Conclusions:

The particle size distribution of the substance was determined as follows: D10 = 2.1 μm, D50 = 14.7 μm and D90 = 116.3 μm (applying 1 bar dispersion (venturi) pressure).
31.3% by volume was determined to be smaller than 10 μm.
The MMAD was calculated to be 25.61 μm.

Description of key information

The particle size distribution of the substance was determined as follows: D10 = 2.1 µm, D50 = 14.7 µm and D90 = 116.3 µm (applying 1 bar dispersion (venturi) pressure).

31.3% by volume was determined to be smaller than 10 µm.

The MMAD was calculated to be 25.61 µm.

Additional information

Determined using Laser Diffraction Analysis.