Calcium nitrite

Oxidising properties

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 January - 9 March 2018 [several physical-chemical studies]

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Good quality study, conducted to GLP.

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)

Deviations:

no

GLP compliance:

yes

Contact with:

powdered cellulose

Sample tested:

4:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

147.6 s

Sample tested:

1:1 sample-to-cellulose ratio

Parameter:

mean burning time

Result:

139.8 s

Sample tested:

reference: 3:7 mixture potassium bromate + cellulose

Parameter:

mean burning time

Result:

96.6 s

Individual run burn times were 152, 143, 156, 142 and 145 seconds for the 4:1 w/w test item:cellulose mixture, 134, 144, 148, 140 and 133 seconds for the 1:1 w/w test item:cellulose mixture, and 99, 101, 92, 96 and 95 for the 3:7 w/w mixture of potassium bromate and cellulose.

 

The burning times for both the 4:1 and 1:1 w/w test item:cellulose mixtures were greater than that of the 3:7 w/w mixture of potassium bromate and cellulose. As such, the test item is not classified as Division 5.1 according to UN Test O.1.

Interpretation of results:

GHS criteria not met

Conclusions:

In a guideline GLP study, calcium nitrite (anhydrous) was found not to be classified as Division 5.1 according to UN Test O.1 (non-oxidising solid).

Executive summary:

In an UN Test O.1 study, conducted according to GLP, calcium nitrite (anhydrous) did not reduce the burning time of cellulose (4:1 and 1:1 w/w sample-to-cellulose ratios) relative to that of the reference formulation (3:7 w/w mixture of potassium bromate and cellulose). As such, it was found not to be classified as Division 5.1 according to UN Test O.1 (non-oxidising solid).

Reference 2

Endpoint:

oxidising liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

No data

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.2 (Test for oxidizing liquids)

Deviations:

not specified

Remarks:

limited documentation of the test method was provided in the summary report

GLP compliance:

not specified

Contact with:

other: no data

Sample tested:

test mixture (not specified)

Parameter:

other: mean maximum pressure rise in 1 minute

Result:

9.2 other: PSI [63.4 kPa]

For the 5 replicates, the maximum pressure rise was 6, 6, 3, 22 and 9 in a time of 1 minute.

Interpretation of results:

GHS criteria not met

Conclusions:

In a guideline study, calcium nitrite (hydrate) was found not to be a liquid oxidiser.

Executive summary:

In a UN Test O.2 study (summary report), calcium nitrite (hydrate) induced a mean maximum pressure rise of only around 63.4 kPa (9.2 PSI) in 1 minute. As such, it did not meet the criteria of a liquid oxidiser as defined by the test specification.

Description of key information

In an UN Test O.1 study, conducted according to GLP, calcium nitrite (anhydrous) did not reduce the burning time of cellulose (4:1 and 1:1 w/w sample-to-cellulose ratios) relative to that of the reference formulation (3:7 w/w mixture of potassium bromate and cellulose). As such, it was found not to be classified as Division 5.1 according to UN Test O.1 (non-oxidising solid) (Sydney, 2018).

In a UN Test O.2 study (summary report), calcium nitrite (hydrate) induced a mean maximum pressure rise of only around 63.4 kPa (9.2 PSI) in 1 minute. As such, it did not meet the criteria of a liquid oxidiser as defined by the test specification (Mendoza and Hanson, 1995).

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

Based on the results of the reliable studies (Mendoza and Hanson, 1995; Sydney, 2018), calcium nitrite does not require classification as an oxidising solid or liquid according to EU CLP criteria (EC 1272/2008).