Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05 Dec 2017 - 09 Jan 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Details on test material:
- Appearance: White powder
- Storage condition of test material: At room temperature

Results and discussion

Vapour pressureopen allclose all
Key result
Temp.:
20 °C
Vapour pressure:
< 0.002 Pa
Key result
Temp.:
25 °C
Vapour pressure:
< 0.004 Pa

Any other information on results incl. tables

Table: Results of the isothermal TGA analysis (test item)

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

logνT

logPT

PT
[Pa]

100

0.0840855

1.00 x 10-5

-5.00

-1.26

5.5 x 10-2

 

0.121614

1.45 x 10-5

-4.84

-1.06

8.8 x 10-2

110

0.236898

2.83 x 10-5

-4.55

-0.69

0.21

 

0.272313

3.25 x 10-5

-4.49

-0.61

0.25

120

0.688436

8.22 x 10-5

-4.09

-0.09

0.81

 

0.694129

8.29 x 10-5

-4.08

-0.09

0.82

130

2.47437

2.95 x 10-4

-3.53

0.62

4.2

 

2.41098

2.88 x 10-4

-3.54

0.60

4.0

The log PT versus 1/T curve for the substance over the range 100-130°C showed poor linearity (correlation coefficient r < 0.99). Extrapolation of the curve to 20°C or 25°C would not give reliable results for the vapour pressure of the substance at these temperatures. Since the weight loss of the test item at 100°C, 110°C, 120°C and 130°C was lower than the weight loss of reference substance hexachlorobenzene at the same temperatures, it was considered that vapour pressure of the substance at 20°C (25°C) is lower than the vapour pressure of hexachlorobenzene at 20°C (25°C).

Applicant's summary and conclusion

Conclusions:
The vapour pressure of the substance at 20°C was determined to be < 0.0015 Pa.
The vapour pressure of the substance at 25°C was determined to be < 0.004 Pa.
Executive summary:

The vapour pressure of the substance was determined using the isothermal thermogravimetric effusion method in a GLP study according to EC A.4, OECD 104 and OPPTS 830.7950.

The constants specific for the experimental arrangement were determined using a set of 5 reference compounds. The log PT versus 1/T curve for the substance over the range 100-130°C showed poor linearity (correlation coefficient r < 0.99). Extrapolation of the curve to 20°C or 25°C would not give reliable results for the vapour pressure of the substance at these temperatures.

From the measured weight losses in the temperature range 100-130°C, the vapour pressure of the substance was determined to be lower than the vapour pressure of reference substance hexachlorobenzene. The vapour pressure of the substance at 20°C and 25°C was concluded to be < 0.0015 Pa and < 0.004 Pa, resp.